MRPL49 Antikörper (N-Term)

Produktnummer ABIN2788326

Produktdetails anti-MRPL49 Antikörper

Target: MRPL49 (Mitochondrial Ribosomal Protein L49 (MRPL49))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MRPL49 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: ESVDEYQFVE RLLPATRIPD PPKHEHYPTP SGWQPPRDPP PNLPYFVRRS

Homologie: Cow: 86%, Dog: 86%, Guinea Pig: 92%, Horse: 92%, Human: 100%, Mouse: 79%, Rabbit: 83%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against MRPL49. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MRPL49

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 166 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu MRPL49

Target: MRPL49 (Mitochondrial Ribosomal Protein L49 (MRPL49))

Andere Bezeichnung: MRPL49 (MRPL49 Produkte)

Synonyme: Aa2-277 antikoerper, BcDNA:RE35556 antikoerper, CG4647 antikoerper, Dmel\\CG4647 antikoerper, MRP-L49 antikoerper, mRpl49 antikoerper, C11orf4 antikoerper, L49mt antikoerper, NOF antikoerper, NOF1 antikoerper, 4833419D18Rik antikoerper, Nof1 antikoerper, mitochondrial ribosomal protein L49 antikoerper, Mrpl49 antikoerper, mRpL49 antikoerper, MRPL49 antikoerper

Hintergrund: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. This gene and the gene for the HRD1 protein use in their respective 3' UTRs some of the same genomic sequence. Pseudogenes corresponding to this gene are found on chromosomes 5q and 8p.
Alias Symbols: C11orf4, L49mt, MGC10656, NOF, NOF1, MRP-L49
Protein Interaction Partner: CEP57, NPM1, METTL18, MRPL52, PRKCDBP, TMEM177, MRPL38, MRPL39, NENF, TIMM10, SCFD1, PPT2, MTHFD1, MGST3, DLST, CDH2, APP, CAND1, COPS5, CUL1, CUL3, TCF3, UBC, ICT1, OXA1L,
Protein Size: 166

Molekulargewicht: 19 kDa

Gen-ID: 740

NCBI Accession: NM_004927, NP_004918

UniProt: Q13405