MRPL49 Antikörper (N-Term)

Produktnummer ABIN2788326

Der Kaninchen Polyklonal anti-MRPL49 Antikörper wird verwendet zum Nachweis von MRPL49 in Proben von Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd und Kaninchen. Er wurde validiert für WB.

Kurzübersicht für MRPL49 Antikörper (N-Term) (ABIN2788326)

Target: MRPL49 (Mitochondrial Ribosomal Protein L49 (MRPL49))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MRPL49 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-MRPL49 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: MRPL49 Antibody - N-terminal region

Sequenz: ESVDEYQFVE RLLPATRIPD PPKHEHYPTP SGWQPPRDPP PNLPYFVRRS

Homologie: Cow: 86%, Dog: 86%, Guinea Pig: 92%, Horse: 92%, Human: 100%, Mouse: 79%, Rabbit: 83%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against MRPL49. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MRPL49

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP60087-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu MRPL49

Target: MRPL49 (Mitochondrial Ribosomal Protein L49 (MRPL49))

Andere Bezeichnung: MRPL49

Hintergrund:

Background Information: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. This gene and the gene for the HRD1 protein use in their respective 3' UTRs some of the same genomic sequence. Pseudogenes corresponding to this gene are found on chromosomes 5q and 8p.

Gene Name: Mitochondrial ribosomal protein L49

Alternative Symbols: NOF, NOF1, L49mt, C11orf4, MRP-L49

Protein Name: 39S ribosomal protein L49, mitochondrial

Molekulargewicht: 19kDa

Gen-ID: 740

NCBI Accession: NP_004918

UniProt: Q13405