C1QA Antikörper (N-Term)

Produktnummer ABIN2788322

Produktdetails anti-C1QA Antikörper

Target: C1QA (Complement Component 1, Q Subcomponent, A Chain (C1QA))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Schwein, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser C1QA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: PGKVGYPGPS GPLGARGIPG IKGTKGSPGN IKDQPRPAFS AIRRNPPMGG

Homologie: Cow: 100%, Dog: 86%, Horse: 86%, Human: 100%, Mouse: 86%, Pig: 86%, Rabbit: 85%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against C1QA. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human C1QA

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 245 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu C1QA

Target: C1QA (Complement Component 1, Q Subcomponent, A Chain (C1QA))

Andere Bezeichnung: C1QA (C1QA Produkte)

Synonyme: zgc:109903 antikoerper, C1QA antikoerper, AI255395 antikoerper, C1q antikoerper, complement C1q A chain antikoerper, complement component 1, q subcomponent, A chain antikoerper, complement component 1, q subcomponent, alpha polypeptide antikoerper, C1QA antikoerper, c1qa antikoerper, C1qa antikoerper

Hintergrund: This gene encodes a major constituent of the human complement subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N terminus and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1. This gene encodes the A-chain polypeptide of human complement subcomponent C1q.
Alias Symbols: -
Protein Interaction Partner: RAC1, SLC25A47, GNPNAT1, UBQLN1, UBQLN2, HIPK3, PIAS2, BAG6, SGTA, PPP1CC, APOA1, PPP1CA, PTX3, C1QBP, CSPG4, C1R, SFTPA1, HRG, FN1, DCN, CR1, C1S, CD93, C1QC, C1QB, COL2A1, APCS, CRP,
Protein Size: 245

Molekulargewicht: 26 kDa

Gen-ID: 712

NCBI Accession: NM_015991, NP_057075

UniProt: P02745

Pathways: Komplementsystem