Maxp1 antikoerper, NORE1 antikoerper, NORE1A antikoerper, NORE1B antikoerper, RAPL antikoerper, RASSF3 antikoerper, 1300019G20Rik antikoerper, AU042887 antikoerper, Nore1 antikoerper, Nore1A antikoerper, Nore1B antikoerper, Rapl antikoerper, Ras association domain family member 5 antikoerper, Ras association (RalGDS/AF-6) domain family member 5 antikoerper, RASSF5 antikoerper, Rassf5 antikoerper
Hintergrund
Rassf5 is a potental tumor suppressor. It seems to be involved in lymphocyte adhesion by linking RAP1A activation upon T-cell receptor or chemokine stimulation to integrin activation. Isoform 2 stimulates lymphocyte polarization and the patch-like distribution of ITGAL/LFA-1, resulting in an enhanced adhesion to ICAM1. Together with RAP1A may participate in regulation of microtubule growth. The association of isoform 2 with activated RAP1A is required for directional movement of endothelial cells during wound healing. It may be involved in regulation of Ras apoptotic function. The RASSF5-STK4/MST1 complex may mediate HRAS1 and KRAS induced apoptosis. Alias Symbols: 1300019G20Rik, AU042887, Maxp1, Nore1, Nore1A, Nore1B, Rapl Protein Interaction Partner: Hras, Protein Size: 413