NCKIPSD Antikörper (Middle Region)
Kurzübersicht für NCKIPSD Antikörper (Middle Region) (ABIN2788096)
Target
Alle NCKIPSD Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Middle Region
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Sequenz
- LVSSVLPVEL ARDMQTDTQD HQKLCYSALI LAMVFSMGEA VPYAHYEHLG
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rat: 100%
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Produktmerkmale
- This is a rabbit polyclonal antibody against NCKIPSD. It was validated on Western Blot.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human NCKIPSD
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 715 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- NCKIPSD (NCK Interacting Protein with SH3 Domain (NCKIPSD))
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Andere Bezeichnung
- NCKIPSD
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Hintergrund
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The protein encoded by this gene is localized exclusively in the cell nucleus. It plays a role in signal transduction, and may function in the maintenance of sarcomeres and in the assembly of myofibrils into sarcomeres. It also plays an important role in stress fiber formation. The gene is involved in therapy-related leukemia by a chromosomal translocation t(3,11)(p21,q23) that involves this gene and the myeloid/lymphoid leukemia gene. Alternative splicing occurs in this locus and two transcript variants encoding distinct isoforms have been identified.
Alias Symbols: AF3P21, DIP, DIP1, MGC23891, ORF1, SPIN90, WASLBP, WISH
Protein Interaction Partner: SORBS3, PSMD9, YWHAB, UBC, GRB2, CRK, FASLG, KHDRBS1, STAC, DMRTB1, ARHGEF7, BAIAP2, YWHAG, NCK2, DLG4, MAPK3, NCK1, WAS, DIAPH2, ITGB1, DIAPH3,
Protein Size: 715 -
Molekulargewicht
- 79 kDa
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Gen-ID
- 51517
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NCBI Accession
- NM_184231, NP_909119
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UniProt
- Q9NZQ3
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Pathways
- Protein targeting to Nucleus
Target
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