NCKIPSD Antikörper

Produktnummer ABIN7231502

Der Kaninchen Polyklonal anti-NCKIPSD Antikörper (ABIN7231502) detektiert spezifisch NCKIPSD in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.

Kurzübersicht für NCKIPSD Antikörper (ABIN7231502)

Target: NCKIPSD (NCK Interacting Protein with SH3 Domain (NCKIPSD))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NCKIPSD Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-NCKIPSD Antikörper

Verwendungszweck: Rabbit Anti-SPN90 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of SPN90 protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human SPN90 protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu NCKIPSD

Target: NCKIPSD (NCK Interacting Protein with SH3 Domain (NCKIPSD))

Andere Bezeichnung: SPN90

Hintergrund: NCK-interacting protein with SH3 domain, 54 kDa VacA-interacting protein, 54 kDa vimentin-interacting protein, VIP54, 90 kDa SH3 protein interacting with Nck, AF3p21, Dia-interacting protein 1, DIP-1, Diaphanous protein-interacting protein, SH3 adapter protein SPIN90, WASP-interacting SH3-domain protein, WISH, Wiskott-Aldrich syndrome protein-interacting proteinThe protein encoded by NCKIPSD (NCK Interacting Protein With SH3 Domain) is localized exclusively in the cell nucleus. It plays a role in signal transduction, and may function in the maintenance of sarcomeres and in the assembly of myofibrils into sarcomeres. It also plays an important role in stress fiber formation. NCKIPSD is involved in therapy-related leukemia by a chromosomal translocation t(3,11)(p21,q23) that involves NCKIPSD and the myeloid/lymphoid leukemia gene. Alternative splicing results in multiple transcript variants of NCKIPSD.

Molekulargewicht: 79kD

Gen-ID: 51517

UniProt: Q9NZQ3

Pathways: Protein targeting to Nucleus