PEN2 Antikörper (N-Term)
Kurzübersicht für PEN2 Antikörper (N-Term) (ABIN2788067)
Target
Alle PEN2 (PSENEN) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Sequenz
- LGGFAFLPFL WLVNIFWFFR EAFLAPAYTE QSQIKGYVWR SAVGFLFWVI
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Homologie
- Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 100%, Zebrafish: 86%
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Produktmerkmale
- This is a rabbit polyclonal antibody against Psenen. It was validated on Western Blot.
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Aufreinigung
- Affinity Purified
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 101 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- PEN2 (PSENEN) (Presenilin Enhancer 2 Homolog (PSENEN))
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Andere Bezeichnung
- Psenen
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Hintergrund
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Psenen is an essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). It probably represents the last step of maturation of gamma-secretase, facilitating endoproteolysis of presenilin and conferring gamma-secretase activity.
Alias Symbols: 1700023M09Rik, MGC102026
Protein Interaction Partner: Psen2, Psen1,
Protein Size: 101 -
Molekulargewicht
- 12 kDa
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Gen-ID
- 66340
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NCBI Accession
- NM_025498, NP_079774
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UniProt
- Q9CQR7
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Pathways
- Notch Signalweg, Neurotrophin Signalübertragung
Target
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