NUMB Antikörper (Middle Region)

Produktnummer ABIN2788065

Der Kaninchen Polyklonal anti-NUMB Antikörper (ABIN2788065) detektiert spezifisch NUMB in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Hund, Pferd, Kaninchen, Meerschweinchen, Saccharomyces cerevisiae und Zebrafisch (Danio rerio).

Kurzübersicht für NUMB Antikörper (Middle Region) (ABIN2788065)

Target: NUMB (Numb Homolog (NUMB))

Reaktivität: Human, Maus, Ratte, Hund, Pferd, Kaninchen, Meerschweinchen, Saccharomyces cerevisiae, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NUMB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-NUMB Antikörper

Bindungsspezifität: Middle Region

Sequenz: VGSSVAPGNT APSPSSPTSP TSDATTSLEM NNPHAIPRRH APIEQLARQG

Homologie: Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Yeast: 91%, Zebrafish: 83%

Produktmerkmale: This is a rabbit polyclonal antibody against NUMB. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human NUMB

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu NUMB

Target: NUMB (Numb Homolog (NUMB))

Andere Bezeichnung: NUMB

Hintergrund: The protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Four transcript variants encoding different isoforms have been found for this gene.
Protein Interaction Partner: TP53, PRKCA, PRKCZ, PRKCE, PRKCB, UBC, SIAH1, RPL3, EGFR, NOTCH1, MDM2, APP, Trp53, Jun, EPS15, Lnx1, ITCH, GLI1, LNX2, AP2A2, PRKCH, DPYSL2, AP2A1, ITGB2, L1CAM, PRKCG, PRKCD, ITGB3, ITGB5, Eps15l1, RALBP1,
Protein Size: 592

Molekulargewicht: 64 kDa

Gen-ID: 8650

Pathways: Cell-Cell Junction Organization