NUMB Antikörper (Middle Region)

Produktnummer ABIN2788065

Dieses Anti-NUMB-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von NUMB in WB. Geeignet für Human, Maus, Ratte, Hund, Pferd, Kaninchen, Meerschweinchen, Saccharomyces cerevisiae und Zebrafisch (Danio rerio).

Kurzübersicht für NUMB Antikörper (Middle Region) (ABIN2788065)

Target: NUMB (Numb Homolog (NUMB))

Reaktivität: Human, Maus, Ratte, Hund, Pferd, Kaninchen, Meerschweinchen, Saccharomyces cerevisiae, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NUMB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-NUMB Antikörper

Bindungsspezifität: Middle Region

Sequenz: VGSSVAPGNT APSPSSPTSP TSDATTSLEM NNPHAIPRRH APIEQLARQG

Homologie: Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Yeast: 91%, Zebrafish: 83%

Produktmerkmale: This is a rabbit polyclonal antibody against NUMB. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human NUMB

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu NUMB

Target: NUMB (Numb Homolog (NUMB))

Andere Bezeichnung: NUMB

Hintergrund: The protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Four transcript variants encoding different isoforms have been found for this gene.
Protein Interaction Partner: TP53, PRKCA, PRKCZ, PRKCE, PRKCB, UBC, SIAH1, RPL3, EGFR, NOTCH1, MDM2, APP, Trp53, Jun, EPS15, Lnx1, ITCH, GLI1, LNX2, AP2A2, PRKCH, DPYSL2, AP2A1, ITGB2, L1CAM, PRKCG, PRKCD, ITGB3, ITGB5, Eps15l1, RALBP1,
Protein Size: 592

Molekulargewicht: 64 kDa

Gen-ID: 8650

Pathways: Cell-Cell Junction Organization