UFD1L Antikörper (Middle Region)

Produktnummer ABIN2788062

Produktdetails anti-UFD1L Antikörper

Target: UFD1L (Ubiquitin Fusion Degradation Protein 1 Homolog (UFD1L))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Hund, Meerschweinchen, Pferd, Zebrafisch (Danio rerio), Rind (Kuh), Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UFD1L Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: NYNEKIYELR VMETKPDKAV SIIECDMNVD FDAPLGYKEP ERQVQHEEST

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 100%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against UFD1L. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human UFD1L

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 307 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu UFD1L

Target: UFD1L (Ubiquitin Fusion Degradation Protein 1 Homolog (UFD1L))

Andere Bezeichnung: UFD1L (UFD1L Produkte)

Synonyme: UFD1 antikoerper, Ufd1 antikoerper, ufd1 antikoerper, wu:fc55f04 antikoerper, zgc:92341 antikoerper, Ufd1l antikoerper, ubiquitin recognition factor in ER associated degradation 1 antikoerper, ubiquitin recognition factor in ER-associated degradation 1 antikoerper, ubiquitin fusion degradation 1 like (yeast) antikoerper, ubiquitin recognition factor in ER associated degradation 1 S homeolog antikoerper, ubiquitin fusion degradation protein 1 homolog antikoerper, Ubiquitin Fusion Degradation (yeast UFD homolog) antikoerper, UFD1 antikoerper, Ufd1 antikoerper, UFD1L antikoerper, ufd1.S antikoerper, ufd1l antikoerper, ufd1 antikoerper, EHI_125920 antikoerper, LOC100166745 antikoerper, LOC100635687 antikoerper, LOC100648660 antikoerper, ufd-1 antikoerper

Hintergrund: The protein encoded by this gene forms a complex with two other proteins, nuclear protein localization-4 and valosin-containing protein, and this complex is necessary for the degradation of ubiquitinated proteins. In addition, this complex controls the disassembly of the mitotic spindle and the formation of a closed nuclear envelope after mitosis. Mutations in this gene have been associated with Catch 22 syndrome as well as cardiac and craniofacial defects. Alternative splicing results in multiple transcript variants encoding different isoforms. A related pseudogene has been identified on chromosome 18.
Alias Symbols: UFD1
Protein Interaction Partner: HUWE1, YOD1, VCP, UBC, SHFM1, SUZ12, BTRC, EZH2, PDCD4, NPLOC4, NFKBIA, NUB1, NEDD8, CAV1, ADRB2, FAF1, TXLNA, UNC45A, VPS33B, UBE3A, UBE2N, PSMD7, SPRTN, UBXN6, GZMK, ERLIN2, ITPR1, PPHLN1, ANAPC2, TIAM2, TAF1C, TP53, SNX1, MASP1, PIK3CA, NGFR, IGHM, F13
Protein Size: 307

Molekulargewicht: 34 kDa

Gen-ID: 7353

NCBI Accession: NM_005659, NP_005650

UniProt: Q92890