RPS27A Antikörper (Middle Region)

Produktnummer ABIN2788060

Der Kaninchen Polyklonal Anti-RPS27A-Antikörper wurde für WB validiert. Er ist geeignet, RPS27A in Proben von Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Schaf, Zebrafisch (Danio rerio), Saccharomyces cerevisiae und Hund zu detektieren.

Kurzübersicht für RPS27A Antikörper (Middle Region) (ABIN2788060)

Target: RPS27A (Ribosomal Protein S27a (RPS27A))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Schaf, Zebrafisch (Danio rerio), Saccharomyces cerevisiae, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RPS27A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-RPS27A Antikörper

Bindungsspezifität: Middle Region

Sequenz: LRGGAKKRKK KSYTTPKKNK HKRKKVKLAV LKYYKVDENG KISRLRRECP

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Yeast: 79%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against RPS27A. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human RPS27A

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 156 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu RPS27A

Target: RPS27A (Ribosomal Protein S27a (RPS27A))

Andere Bezeichnung: RPS27A

Hintergrund: Ubiquitin, a highly conserved protein that has a major role in targeting cellular proteins for degradation by the 26S proteosome, is synthesized as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin fused to an unrelated protein. This gene encodes a fusion protein consisting of ubiquitin at the N terminus and ribosomal protein S27a at the C terminus. When expressed in yeast, the protein is post-translationally processed, generating free ubiquitin monomer and ribosomal protein S27a. Ribosomal protein S27a is a component of the 40S subunit of the ribosome and belongs to the S27AE family of ribosomal proteins. It contains C4-type zinc finger domains and is located in the cytoplasm. Pseudogenes derived from this gene are present in the genome. As with ribosomal protein S27a, ribosomal protein L40 is also synthesized as a fusion protein with ubiquitin, similarly, ribosomal protein S30 is synthesized as a fusion protein with the ubiquitin-like protein fubi. Multiple alternatively spliced transcript variants that encode the same proteins have been identified.
Alias Symbols: CEP80, UBA80, UBCEP1, UBCEP80, UBC, S27A
Protein Interaction Partner: CALCOCO2, DAZAP2, UBC, MDM2, TRIM25, EED, TP53, RNF11, rev, TUBA4A, PARK2, CDK2, PAN2, ZNF512B, SMAD2, ITGA4, FN1, CDK11B, UBL4A, VCAM1, RPL21, RPL19, RPL18A, RPL18, RPL17, RPL15, RPL11, RPL9, RPL7A, RPL6, RPL5, RPL4, RPL37A, RPL31, RPL24, RPL23A, RPL22,
Protein Size: 156

Molekulargewicht: 18 kDa

Gen-ID: 6233

NCBI Accession: NM_002954, NP_002945

UniProt: P62979

Pathways: Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Activation of Innate immune Response, Mitotic G1-G1/S Phases, DNA Replication, Toll-Like Receptors Cascades, Synthesis of DNA, EGFR Downregulation