UBL4A Antikörper (Middle Region)
Kurzübersicht für UBL4A Antikörper (Middle Region) (ABIN2788049)
Target
Alle UBL4A Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Middle Region
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Sequenz
- EGEAQRLADS PPPQVWQLIS KVLARHFSAA DASRVLEQLQ RDYERSLSRL
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Homologie
- Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 93%, Yeast: 83%
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Produktmerkmale
- This is a rabbit polyclonal antibody against UBL4A. It was validated on Western Blot.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human UBL4A
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 157 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- UBL4A (Ubiquitin-Like 4A (UBL4A))
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Andere Bezeichnung
- UBL4A
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Hintergrund
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UBL4A is a component of the BAT3 complex, a multiprotein complex involved in the post-translational delivery of tail-anchored (TA) membrane proteins to the endoplasmic reticulum membrane. UBL4A is the TA membrane proteins, also named type II transmembrane proteins, contain a single C-terminal transmembrane region. The complex acts by facilitating TA proteins capture by ASNA1/TRC40: it is recruited to ribosomes synthesizing membrane proteins, interacts with the transmembrane region of newly released TA proteins, and transfers them to ASNA1/TRC40 for targeting.
Alias Symbols: DX254E, DXS254E, G6PD, GDX, UBL4, GET5, MDY2, TMA24
Protein Interaction Partner: MEOX2, HUWE1, TRAF4, CDCA7L, FAF1, VAPB, SGTA, SHFM1, UBC, CDK18, HIPK4, FAF2, UQCRC1, UBE2G2, UBA52, GET4, RAB14, PTPLAD1, CD320, HSD17B12, GEMIN4, UBQLN1, PABPC1, FAM162A, PRPF31, GEMIN5, METTL21B, RPL36, CORO1C, RPL13A, PHB2, DDX20, ERLIN2, RER1, RAB35
Protein Size: 157 -
Molekulargewicht
- 18 kDa
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Gen-ID
- 8266
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NCBI Accession
- NM_014235, NP_055050
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UniProt
- B7NZQ9
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Pathways
- Ubiquitin Proteasome Pathway
Target
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