VCP Antikörper (C-Term)
Kurzübersicht für VCP Antikörper (C-Term) (ABIN2788042)
Target
Alle VCP Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Sequenz
- EMFAQTLQQS RGFGSFRFPS GNQGGAGPSQ GSGGGTGGSV YTEDNDDDLY
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
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Produktmerkmale
- This is a rabbit polyclonal antibody against VCP. It was validated on Western Blot.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human VCP
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 806 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- VCP (Valosin Containing Protein (VCP))
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Andere Bezeichnung
- VCP
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Hintergrund
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The protein encoded by this gene is a member of a family that includes putative ATP-binding proteins involved in vesicle transport and fusion, 26S proteasome function, and assembly of peroxisomes. This protein, as a structural protein, is associated with clathrin, and heat-shock protein Hsc70, to form a complex. It has been implicated in a number of cellular events that are regulated during mitosis, including homotypic membrane fusion, spindle pole body function, and ubiquitin-dependent protein degradation.
Alias Symbols: IBMPFD, MGC131997, MGC148092, MGC8560, TERA, p97, ALS14
Protein Interaction Partner: AMFR, UBXN2B, CEP19, FAM104A, UBC, ATXN3, FUS, DTNB, WDYHV1, VCP, LNX1, PSMA1, UBXN1, ASPSCR1, NSFL1C, RPL9, UBOX5, HUWE1, ISG15, ATG5, PLAA, RNF8, YOD1, VAPA, RPL23, GTF3C5, ACTB, PPP3CA, PPM1B, PHKG2, MDM2, CDK2, CCNB1, AR, OTU1, TUBB, UBXN2A, H2AFV, FB
Protein Size: 806 -
Molekulargewicht
- 89 kDa
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Gen-ID
- 7415
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NCBI Accession
- NM_007126, NP_009057
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UniProt
- P55072
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Pathways
- ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Ubiquitin Proteasome Pathway
Target
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