KNG1 Antikörper (N-Term)

Produktnummer ABIN2787975

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch KNG1 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Ratte und Schwein.

Kurzübersicht für KNG1 Antikörper (N-Term) (ABIN2787975)

Target: KNG1 (Kininogen 1 (KNG1))

Reaktivität: Human, Ratte, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KNG1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-KNG1 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: KNG1 Antibody - N-terminal region

Sequenz: ALKKYNSQNQ SNNQFVLYRI TEATKTVGSD TFYSFKYEIK EGDCPVQSGK

Homologie: Human: 100%, Pig: 79%, Rat: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against KNG1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human KNG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP59203-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu KNG1

Target: KNG1 (Kininogen 1 (KNG1))

Andere Bezeichnung: KNG1

Hintergrund:

Background Information: Kininogens are inhibitors of thiol proteases. HMW-kininogen plays an important role in blood coagulation by helping to position optimally prekallikrein and factor XI next to factor XII and inhibits the thrombin- and plasmin-induced aggregation of thrombocytes. The active peptide bradykinin that is released from HMW-kininogen shows a variety of physiological effects such as influence in smooth muscle contraction, induction of hypotension, natriuresis and diuresis, etc.

Gene Name: kininogen 1

Alternative Symbols: BK, BDK, KNG, HMWK

Protein Name: Kininogen-1 Ensembl ENSP00000396025

Molekulargewicht: 43kDa

Gen-ID: 3827

NCBI Accession: NP_001159923

UniProt: C9JEX1

Pathways: ACE Inhibitor Pathway, Glycosaminoglycan Metabolic Process