TIMP1 Antikörper (N-Term)

Produktnummer ABIN2787966

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch TIMP1 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Ratte, Maus, Kaninchen, Hund, Pferd, Schaf, Rind (Kuh), Ziege und Meerschweinchen.

Kurzübersicht für TIMP1 Antikörper (N-Term) (ABIN2787966)

Target: TIMP1 (TIMP Metallopeptidase Inhibitor 1 (TIMP1))

Reaktivität: Human, Ratte, Maus, Kaninchen, Hund, Pferd, Schaf, Rind (Kuh), Ziege, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TIMP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-TIMP1 Antikörper

Bindungsspezifität: N-Term

Sequenz: QRYEIKMTKM YKGFQALGDA ADIRFVYTPA MESVCGYFHR SHNRSEEFLI

Homologie: Cow: 93%, Dog: 86%, Goat: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 79%, Rabbit: 79%, Rat: 79%, Sheep: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against TIMP1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human TIMP1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu TIMP1

Target: TIMP1 (TIMP Metallopeptidase Inhibitor 1 (TIMP1))

Andere Bezeichnung: TIMP1

Hintergrund: This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction.
Alias Symbols: CLGI, EPA, HCI, TIMP
Protein Interaction Partner: UBC, FBXO6, MYOC, ZBTB16, RECQL5, ECH1, EEF1B2, MMP3, CD63, MMP2, MMP1,
Protein Size: 207

Molekulargewicht: 23 kDa

Gen-ID: 7076

NCBI Accession: NM_003254, NP_003245

UniProt: Q6FGX5