TIM3 Antikörper (C-Term)

Produktnummer ABIN2787957

Der Kaninchen Polyklonal Anti-TIM3-Antikörper wurde für WB validiert. Er ist geeignet, TIM3 in Proben von Human, Hund, Rind (Kuh) und Pferd zu detektieren.

Kurzübersicht für TIM3 Antikörper (C-Term) (ABIN2787957)

Target: TIM3 (TIM 3) (Hepatitis A Virus Cellular Receptor 2 (TIM 3))

Reaktivität: Human, Hund, Rind (Kuh), Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TIM3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-TIM3 Antikörper

Bindungsspezifität: C-Term

Sequenz: IGIYIGAGIC AGLALALIFG ALIFKWYSHS KEKIQNLSLI SLANLPPSGL

Homologie: Cow: 83%, Dog: 82%, Horse: 91%, Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against HAVCR2. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human HAVCR2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 301 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu TIM3

Target: TIM3 (TIM 3) (Hepatitis A Virus Cellular Receptor 2 (TIM 3))

Andere Bezeichnung: HAVCR2

Substanzklasse: Virus

Hintergrund: HAVCR2 regulates macrophage activation. HAVCR2 inhibits T-helper type 1 lymphocyte (Th1)-mediated auto- and alloimmune responses and promotes immunological tolerance. HAVCR2 may be also involved in T-cell homing. HAVCR2 is the receptor for LGALS9.
Alias Symbols: FLJ14428, KIM-3, TIM3, TIMD3, Tim-3, TIMD-3, HAVcr-2
Protein Interaction Partner: BAG6, LCK, APP, HAVCR2,
Protein Size: 301

Molekulargewicht: 33 kDa

Gen-ID: 84868

NCBI Accession: NM_032782, NP_116171

UniProt: Q8TDQ0

Pathways: Regulation of Lipid Metabolism by PPARalpha, Cancer Immune Checkpoints