LAG3 Antikörper (C-Term)

Produktnummer ABIN2787950

Dieses Anti-LAG3-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von LAG3 in WB. Geeignet für Human, Maus, Ratte, Kaninchen und Saccharomyces cerevisiae.

Kurzübersicht für LAG3 Antikörper (C-Term) (ABIN2787950)

Target: LAG3 (Lymphocyte-Activation Gene 3 (LAG3))

Reaktivität: Human, Maus, Ratte, Kaninchen, Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LAG3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-LAG3 Antikörper

Bindungsspezifität: C-Term

Sequenz: GFHLWRRQWR PRRFSALEQG IHPPQAQSKI EELEQEPEPE PEPEPEPEPE

Homologie: Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 100%, Yeast: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against LAG3. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human LAG3

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 525 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu LAG3

Target: LAG3 (Lymphocyte-Activation Gene 3 (LAG3))

Andere Bezeichnung: LAG3

Hintergrund: Lymphocyte-activation protein 3 belongs to Ig superfamily and contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4.
Alias Symbols: CD223
Protein Interaction Partner: CENPJ, CEBPZ,
Protein Size: 525

Molekulargewicht: 55 kDa

Gen-ID: 3902

NCBI Accession: NM_002286, NP_002277

UniProt: P18627

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints