CD3 epsilon Antikörper (Middle Region)
Kurzübersicht für CD3 epsilon Antikörper (Middle Region) (ABIN2787934)
Target
Alle CD3 epsilon (CD3E) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Middle Region
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Sequenz
- QYPGSEILWQ HNDKNIGGDE DDKNIGSDED HLSLKEFSEL EQSGYYVCYP
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Homologie
- Human: 100%
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Produktmerkmale
- This is a rabbit polyclonal antibody against CD3E. It was validated on Western Blot.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human CD3E
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anti-CD3 epsilon (CD3E) (AA 157-207) antibody
CD3E Reaktivität: Human FACS, WB, IHC, IP, IF (p), mIF Wirt: Kaninchen Monoclonal BL-298-5D12 unconjugated Recombinant Antibody
anti-CD3 epsilon (CD3E) (AA 23-207) antibodyCD3E Reaktivität: Human, Maus, Ratte, Huhn WB, IHC, IF, ICC, IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-CD3 epsilon (CD3E) (AA 25-207) antibodyCD3E Reaktivität: Human WB, IHC, IP Wirt: Kaninchen Polyclonal unconjugated
anti-CD3 epsilon (CD3E) (C-Term) antibodyCD3E Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-CD3 epsilon (CD3E) (C-Term) antibodyCD3E Reaktivität: Human, Maus, Ratte WB, IHC, IF, ELISA, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-CD3 epsilon (CD3E) antibodyCD3E Reaktivität: Human, Maus, Ratte WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-CD3 epsilon (CD3E) (AA 156-168), (Cytoplasmic Domain) antibodyCD3E Reaktivität: Human, Ratte, Schwein, Rind (Kuh), Pferd, Kaninchen, Meerschweinchen, Huhn FACS, WB, IF Wirt: Maus Monoclonal PC3-188A unconjugated
anti-CD3 epsilon (CD3E) (AA 23-119) antibodyCD3E Reaktivität: Human FACS, WB, IHC, ELISA Wirt: Maus Monoclonal C3e-1931 unconjugated
anti-CD3 epsilon (CD3E) antibodyCD3E Reaktivität: Human, Maus, Ratte FACS, IF, Func Wirt: Maus Monoclonal RIV9 unconjugated
anti-CD3 epsilon (CD3E) antibodyCD3E Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Chimeric YTH 12-5 unconjugated Recombinant Antibody
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 207 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- CD3 epsilon (CD3E)
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Andere Bezeichnung
- CD3E
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Hintergrund
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The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women.
Alias Symbols: FLJ18683, T3E, TCRE
Protein Interaction Partner: UBC, CSK, ZAP70, SNTA1, PTPN22, PIK3R2, PIK3R1, LAT, LCK, CD38, CD247, CD3G, TRAT1, NCK2, UNC119, SHC1, NCK1, SYK, CD3D, NCL, CD79B, TOP2B, CD3EAP, JAK3,
Protein Size: 207 -
Molekulargewicht
- 23 kDa
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Gen-ID
- 916
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NCBI Accession
- NM_000733, NP_000724
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UniProt
- P07766
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Pathways
- T-Zell Rezeptor Signalweg, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway
Target
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