CD27 Antikörper (C-Term)

Produktnummer ABIN2787932

Der Kaninchen Polyklonal Anti-CD27-Antikörper wurde für WB validiert. Er ist geeignet, CD27 in Proben von Human, Maus, Ratte, Schwein, Rind (Kuh), Hund, Pferd, Meerschweinchen und Kaninchen zu detektieren.

Kurzübersicht für CD27 Antikörper (C-Term) (ABIN2787932)

Target: CD27 (CD27 Molecule (CD27))

Reaktivität: Human, Maus, Ratte, Schwein, Rind (Kuh), Hund, Pferd, Meerschweinchen, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD27 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CD27 Antikörper

Bindungsspezifität: C-Term

Sequenz: LHQRRKYRSN KGESPVEPAE PCRYSCPREE EGSTIPIQED YRKPEPACSP

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 75%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 92%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against CD27. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CD27

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 260 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CD27

Target: CD27 (CD27 Molecule (CD27))

Andere Bezeichnung: CD27

Hintergrund: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.
Alias Symbols: MGC20393, S152, T14, TNFRSF7, Tp55
Protein Interaction Partner: TRAF2, CD70, ELAVL1, UHRF2, SIVA1, TRAF5, TRAF3, TRAF1, CD5,
Protein Size: 260

Molekulargewicht: 27 kDa

Gen-ID: 939

NCBI Accession: NM_001242, NP_001233

UniProt: P26842

Pathways: Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints