Caspase 7 Antikörper (N-Term)

Produktnummer ABIN2787907

Der Kaninchen Polyklonal anti-Caspase 7 Antikörper (ABIN2787907) detektiert spezifisch Caspase 7 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Schwein, Hund, Kaninchen, Meerschweinchen, Pferd, Zebrafisch (Danio rerio), Rind (Kuh) und Ziege.

Kurzübersicht für Caspase 7 Antikörper (N-Term) (ABIN2787907)

Target: Caspase 7 (CASP7) (Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7))

Reaktivität: Human, Maus, Ratte, Schwein, Hund, Kaninchen, Meerschweinchen, Pferd, Zebrafisch (Danio rerio), Rind (Kuh), Ziege

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Caspase 7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Caspase 7 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: CASP7 Antibody - N-terminal region

Sequenz: NNKNFDKVTG MGVRNGTDKD AEALFKCFRS LGFDVIVYND CSCAKMQDLL

Homologie: Cow: 100%, Dog: 100%, Goat: 93%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CASP7

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP58995-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu Caspase 7

Target: Caspase 7 (CASP7) (Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7))

Andere Bezeichnung: CASP7

Hintergrund:

Background Information: This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of this caspase is cleaved by caspase 3 and 10. It is activated upon cell death stimuli and induces apoptosis. Alternative splicing results in four transcript variants, encoding three distinct isoforms.

Gene Name: Caspase 7, apoptosis-related cysteine peptidase

Alternative Symbols: MCH3, CMH-1, LICE2, CASP-7, ICE-LAP3

Protein Name: Caspase-7

Molekulargewicht: 37kDa

Gen-ID: 840

NCBI Accession: NP_203124

UniProt: P55210

Pathways: Apoptose, Caspase Kaskade in der Apoptose, Positive Regulation of Endopeptidase Activity