Caspase 7 Antikörper (N-Term)
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- Target Alle Caspase 7 (CASP7) Antikörper anzeigen
- Caspase 7 (CASP7) (Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Maus, Ratte, Schwein, Hund, Kaninchen, Meerschweinchen, Pferd, Zebrafisch (Danio rerio), Rind (Kuh), Ziege
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Caspase 7 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- NNKNFDKVTG MGVRNGTDKD AEALFKCFRS LGFDVIVYND CSCAKMQDLL
- Homologie
- Cow: 100%, Dog: 100%, Goat: 93%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human CASP7
- Top Product
- Discover our top product CASP7 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 336 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- Caspase 7 (CASP7) (Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7))
- Andere Bezeichnung
- CASP7 (CASP7 Produkte)
- Synonyme
- xCaspase-7 antikoerper, caspase-7 antikoerper, caspase7 antikoerper, cmh-1 antikoerper, ice-lap3 antikoerper, mch3 antikoerper, CASP7 antikoerper, AI314680 antikoerper, CMH-1 antikoerper, ICE-IAP3 antikoerper, Mch3 antikoerper, mCASP-7 antikoerper, CASP-7 antikoerper, ICE-LAP3 antikoerper, LICE2 antikoerper, MCH3 antikoerper, Caspase-7 antikoerper, MCH3/SCA-2 antikoerper, SCA-2 antikoerper, caspase 7 antikoerper, caspase-7 antikoerper, caspase 7 S homeolog antikoerper, CASP7 antikoerper, xcaspase-7 antikoerper, casp7 antikoerper, casp7.S antikoerper, Casp7 antikoerper
- Hintergrund
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This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of this caspase is cleaved by caspase 3 and 10. It is activated upon cell death stimuli and induces apoptosis. Alternative splicing results in four transcript variants, encoding three distinct isoforms.
Alias Symbols: CMH-1, ICE-LAP3, MCH3
Protein Interaction Partner: PTGES3, BAX, PARP1, SAT1, CRYAB, XIAP, RPS6KA1, CTSA, PEPD, MVD, GNS, GBP2, EEF2, CAPN1, CNDP2, GINS2, EIF4H, GZMB, ROCK1, DFFA, CASP9, CASP7, CASP3, ARHGDIA, VIM, STAT1, SPTAN1, CLSPN, PLA2G4B, RB1, UBC, BIRC2, CCT2, VCP, SP1, BIRC3, BIRC6, COPS6, TERF1,
Protein Size: 336 - Molekulargewicht
- 37 kDa
- Gen-ID
- 840
- NCBI Accession
- NM_033338, NP_203124
- UniProt
- P55210
- Pathways
- Apoptose, Caspase Kaskade in der Apoptose, Positive Regulation of Endopeptidase Activity
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