Caspase 7 Antikörper (N-Term)

Produktnummer ABIN2787907

Dieses Anti-Caspase 7-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Caspase 7 in WB. Geeignet für Human, Maus, Ratte, Schwein, Hund, Kaninchen, Meerschweinchen, Pferd, Zebrafisch (Danio rerio), Rind (Kuh) und Ziege.

Kurzübersicht für Caspase 7 Antikörper (N-Term) (ABIN2787907)

Target: Caspase 7 (CASP7) (Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7))

Reaktivität: Human, Maus, Ratte, Schwein, Hund, Kaninchen, Meerschweinchen, Pferd, Zebrafisch (Danio rerio), Rind (Kuh), Ziege

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Caspase 7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Caspase 7 Antikörper

Bindungsspezifität: N-Term

Sequenz: NNKNFDKVTG MGVRNGTDKD AEALFKCFRS LGFDVIVYND CSCAKMQDLL

Homologie: Cow: 100%, Dog: 100%, Goat: 93%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CASP7

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 336 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Caspase 7

Target: Caspase 7 (CASP7) (Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7))

Andere Bezeichnung: CASP7

Hintergrund: This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of this caspase is cleaved by caspase 3 and 10. It is activated upon cell death stimuli and induces apoptosis. Alternative splicing results in four transcript variants, encoding three distinct isoforms.
Alias Symbols: CMH-1, ICE-LAP3, MCH3
Protein Interaction Partner: PTGES3, BAX, PARP1, SAT1, CRYAB, XIAP, RPS6KA1, CTSA, PEPD, MVD, GNS, GBP2, EEF2, CAPN1, CNDP2, GINS2, EIF4H, GZMB, ROCK1, DFFA, CASP9, CASP7, CASP3, ARHGDIA, VIM, STAT1, SPTAN1, CLSPN, PLA2G4B, RB1, UBC, BIRC2, CCT2, VCP, SP1, BIRC3, BIRC6, COPS6, TERF1,
Protein Size: 336

Molekulargewicht: 37 kDa

Gen-ID: 840

NCBI Accession: NM_033338, NP_203124

UniProt: P55210

Pathways: Apoptose, Caspase Kaskade in der Apoptose, Positive Regulation of Endopeptidase Activity