Caspase 2 Antikörper (Middle Region)

Produktnummer ABIN2787902

Produktdetails anti-Caspase 2 Antikörper

Target: Caspase 2 (CASP2) (Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Hund, Meerschweinchen, Rind (Kuh), Pferd, Schwein, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Caspase 2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: DNANCPSLQN KPKMFFIQAC RGDETDRGVD QQDGKNHTQS PGCEESDAGK

Homologie: Cow: 91%, Dog: 93%, Guinea Pig: 83%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against Casp2. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Mouse Casp2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 452 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Caspase 2

Target: Caspase 2 (CASP2) (Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2))

Andere Bezeichnung: Casp2 (CASP2 Produkte)

Synonyme: xCaspase-2 antikoerper, Caspase-2 antikoerper, ICH-1 antikoerper, Nedd2 antikoerper, CASP-2 antikoerper, ICH1 antikoerper, NEDD-2 antikoerper, NEDD2 antikoerper, PPP1R57 antikoerper, ICH-1L/1S antikoerper, ICH1L1S antikoerper, caspase 2 antikoerper, caspase 2 L homeolog antikoerper, caspase-2 antikoerper, CASP2 antikoerper, casp2.L antikoerper, CpipJ_CPIJ008254 antikoerper, Casp2 antikoerper

Hintergrund: Casp2 is involved in the activation cascade of caspases responsible for apoptosis execution. It might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival. It may be important in multistep carcinogenesis.
Alias Symbols: Caspase-2, ICH-1, Nedd2
Protein Interaction Partner: Casp2,
Protein Size: 452

Molekulargewicht: 51 kDa

Gen-ID: 12366

NCBI Accession: NM_007610, NP_031636

UniProt: P29594

Pathways: Apoptose, Caspase Kaskade in der Apoptose, Neurotrophin Signalübertragung