DRAM Antikörper (N-Term)

Produktnummer ABIN2787866

Der Kaninchen Polyklonal anti-DRAM Antikörper wird verwendet zum Nachweis von DRAM in Proben von Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Kaninchen und Meerschweinchen. Er wurde validiert für WB.

Kurzübersicht für DRAM Antikörper (N-Term) (ABIN2787866)

Target: DRAM (DRAM1) (DNA-Damage Regulated Autophagy Modulator 1 (DRAM1))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Kaninchen, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DRAM Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-DRAM Antikörper

Bindungsspezifität: N-Term

Sequenz: TMYTRYKIVQ KQNQTCYFST PVFNLVSLVL GLVGCFGMGI VANFQELAVP

Homologie: Cow: 92%, Dog: 92%, Guinea Pig: 92%, Horse: 92%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against DRAM. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human DRAM

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 238 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu DRAM

Target: DRAM (DRAM1) (DNA-Damage Regulated Autophagy Modulator 1 (DRAM1))

Andere Bezeichnung: DRAM

Hintergrund: This gene is regulated as part of the p53 tumor suppressor pathway. The gene encodes a lysosomal membrane protein that is required for the induction of autophagy by the pathway. Decreased transcriptional expression of this gene is associated with various tumors. This gene has a pseudogene on chromosome 4.
Alias Symbols: DRAM, FLJ11259
Protein Interaction Partner: C1orf21, APP,
Protein Size: 238

Molekulargewicht: 26 kDa

Gen-ID: 55332

NCBI Accession: NM_018370, NP_060840

UniProt: Q8N682