BNIP3L/NIX Antikörper (Middle Region)

Produktnummer ABIN2787863

Der Kaninchen Polyklonal anti-BNIP3L/NIX Antikörper wird verwendet zum Nachweis von BNIP3L/NIX in Proben von Human, Maus, Ratte, Hund, Pferd, Rind (Kuh), Meerschweinchen, Schwein und Kaninchen. Er wurde validiert für WB.

Kurzübersicht für BNIP3L/NIX Antikörper (Middle Region) (ABIN2787863)

Target: BNIP3L/NIX (BNIP3L) (BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like (BNIP3L))

Reaktivität: Human, Maus, Ratte, Hund, Pferd, Rind (Kuh), Meerschweinchen, Schwein, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BNIP3L/NIX Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-BNIP3L/NIX Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: Bnip3l Antibody - middle region

Sequenz: CDSPSPQEDG QIMFDVEMHT SRDHSSQSEE EVVEGEKEVE ALKKSADWVS

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against Bnip3l. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP58878-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu BNIP3L/NIX

Target: BNIP3L/NIX (BNIP3L) (BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like (BNIP3L))

Andere Bezeichnung: Bnip3l

Hintergrund:

Background Information: Bnip3l induces apoptosis. It interacts with viral and cellular anti-apoptosis proteins. It can overcome the suppressors BCL-2 and BCL-XL, although high levels of BCL-XL expression will inhibit apoptosis. It inhibits apoptosis induced by BNIP3. It is involved in mitochondrial quality control via its interaction with SPATA18/MIEAP: in response to mitochondrial damage, participates to mitochondrial protein catabolic process (also named MALM) leading to the degradation of damaged proteins inside mitochondria. Bnip3l may function as a tumor suppressor.

Gene Name: BCL2/adenovirus E1B interacting protein 3-like

Alternative Symbols: N, Nix, Nip3L, C86132, D14Ertd719, D14Ertd719e

Protein Name: BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like

Molekulargewicht: 24kDa

Gen-ID: 12177

NCBI Accession: NP_033891

UniProt: Q9Z2F7

Pathways: Autophagie