ATG4C Antikörper (Middle Region)

Produktnummer ABIN2787855

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch ATG4C in WB. Es zeigt Reaktivität gegenüber Proben von Human, Rind (Kuh), Pferd und Hund.

Kurzübersicht für ATG4C Antikörper (Middle Region) (ABIN2787855)

Target: ATG4C (Autophagy related 4C Cysteine Peptidase (ATG4C))

Reaktivität: Human, Rind (Kuh), Pferd, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ATG4C Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ATG4C Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: ATG4C Antibody - middle region

Sequenz: TISLKETIGK YSDDHEMRNE VYHRKIISWF GDSPLALFGL HQLIEYGKKS

Homologie: Cow: 75%, Dog: 91%, Horse: 86%, Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against ATG4C. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ATG4C

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP58863-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu ATG4C

Target: ATG4C (Autophagy related 4C Cysteine Peptidase (ATG4C))

Andere Bezeichnung: ATG4C

Hintergrund:

Background Information: Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding the same protein, have been characterized.

Gene Name: ATG4 autophagy related 4 homolog C (S. cerevisiae)

Alternative Symbols: APG4C, AUTL1, AUTL3, APG4-C

Protein Name: Cysteine protease ATG4C

Molekulargewicht: 52kDa

Gen-ID: 84938

NCBI Accession: NP_835739

UniProt: Q96DT6

Pathways: Autophagie