ATG4C Antikörper (Middle Region)

Produktnummer ABIN2787855

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch ATG4C in WB. Er zeigt eine Reaktivität gegenüber Human, Rind (Kuh), Pferd und Hund.

Kurzübersicht für ATG4C Antikörper (Middle Region) (ABIN2787855)

Target: ATG4C (Autophagy related 4C Cysteine Peptidase (ATG4C))

Reaktivität: Human, Rind (Kuh), Pferd, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ATG4C Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ATG4C Antikörper

Bindungsspezifität: Middle Region

Sequenz: TISLKETIGK YSDDHEMRNE VYHRKIISWF GDSPLALFGL HQLIEYGKKS

Homologie: Cow: 75%, Dog: 91%, Horse: 86%, Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against ATG4C. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ATG4C

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 458 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ATG4C

Target: ATG4C (Autophagy related 4C Cysteine Peptidase (ATG4C))

Andere Bezeichnung: ATG4C

Hintergrund: Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding the same protein, have been characterized.
Alias Symbols: APG4-C, APG4C, AUTL1, AUTL3, FLJ14867
Protein Interaction Partner: UBC, SPTLC1, SMC1A, USP11, PSMD2, PSMC5, PSMC4, PSMC2, PSMC1, PRKDC,
Protein Size: 458

Molekulargewicht: 52 kDa

Gen-ID: 84938

NCBI Accession: NM_178221, NP_835739

UniProt: Q96DT6

Pathways: Autophagie