Thrombopoietin Antikörper (Middle Region)

Produktnummer ABIN2787808

Es gibt 1 Publikation für dieses Produkt. Der Kaninchen Polyklonal anti-Thrombopoietin Antikörper wird verwendet zum Nachweis von Thrombopoietin in Proben von Human, Hund und Kaninchen. Er wurde validiert für WB.

Kurzübersicht für Thrombopoietin Antikörper (Middle Region) (ABIN2787808)

Target: Thrombopoietin (THPO)

Reaktivität: Human, Hund, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Thrombopoietin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Thrombopoietin Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: THPO Antibody - middle region

Sequenz: NLQPGYSPSP THPPTGQYTL FPLPPTLPTP VVQLHPLLPD PSAPTPTPTS

Homologie: Dog: 83%, Human: 100%, Rabbit: 90%

Produktmerkmale: This is a rabbit polyclonal antibody against THPO. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human THPO

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP58735-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-Thrombopoietin Antikörper (ABIN2787808)

Baker, Gray, Wright, Fitzsimons, Nimmo, Lowry, Mutrie,: "The effect of a pedometer-based community walking intervention "Walking for Wellbeing in the West" on physical activity levels and health outcomes: a 12-week randomized controlled trial." in: The international journal of behavioral nutrition and physical activity, Vol. 5, pp. 44, (2008) (PubMed).

Details zu Thrombopoietin

Target: Thrombopoietin (THPO)

Andere Bezeichnung: THPO

Hintergrund:

Background Information: Megakaryocytopoiesis is the cellular development process that leads to platelet production. THPO is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. THPO is the ligand for MLP/C_MPL, the product of myeloproliferative leukemia virus oncogene.Megakaryocytopoiesis is the cellular development process that leads to platelet production. The protein encoded by this gene is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. This protein is the ligand for MLP/C_MPL, the product of myeloproliferative leukemia virus oncogene. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: Thrombopoietin

Alternative Symbols: ML, TPO, MGDF, MKCSF, MPLLG, THCYT1

Protein Name: Thrombopoietin

Molekulargewicht: 35kDa

Gen-ID: 7066

NCBI Accession: NP_000451

UniProt: P40225

Pathways: JAK-STAT Signalweg, Hormone Activity