Thrombopoietin Antikörper (Middle Region)

Produktnummer ABIN2787807

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Thrombopoietin in WB. Es zeigt Reaktivität gegenüber Proben von Human und Pferd.

Kurzübersicht für Thrombopoietin Antikörper (Middle Region) (ABIN2787807)

Target: Thrombopoietin (THPO)

Reaktivität: Human, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Thrombopoietin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Thrombopoietin Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: THPO Antibody - middle region

Sequenz: HELLNGTRGL FPGPSRRTLG APDISSGTSD TGSLPPNLQP GYSPSPTHPP

Homologie: Horse: 79%, Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against THPO. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human THPO

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP58734-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu Thrombopoietin

Target: Thrombopoietin (THPO)

Andere Bezeichnung: THPO

Hintergrund:

Background Information: Megakaryocytopoiesis is the cellular development process that leads to platelet production. THPO is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. THPO is the ligand for MLP/C_MPL, the product of myeloproliferative leukemia virus oncogene.Megakaryocytopoiesis is the cellular development process that leads to platelet production. The protein encoded by this gene is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. This protein is the ligand for MLP/C_MPL, the product of myeloproliferative leukemia virus oncogene. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: Thrombopoietin

Alternative Symbols: ML, TPO, MGDF, MKCSF, MPLLG, THCYT1

Protein Name: Thrombopoietin

Molekulargewicht: 35kDa

Gen-ID: 7066

NCBI Accession: NP_000451

UniProt: P40225

Pathways: JAK-STAT Signalweg, Hormone Activity