Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch UBAC1 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Hund, Meerschweinchen, Rind (Kuh) und Zebrafisch (Danio rerio).
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1 mg/mL
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeat freeze-thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target
UBAC1
(UBA Domain Containing 1 (UBAC1))
Andere Bezeichnung
UBAC1
Hintergrund
UBAC1 is a non-catalytic subunit of the KPC complex that acts as E3 ubiquitin-protein ligase. It is required for poly-ubiquitination and proteasome-mediated degradation of CDKN1B during G1 phase of the cell cycle. Alias Symbols: GBDR1, RP11-432J22.3, UBADC1 Protein Interaction Partner: TRIM39, TRIM2, DAZAP2, UBC, HTT, UNC119B, VPS25, UTP6, RPS6KA6, TWF2, USP7, TCEA1, APP, AIRE, CSNK2A1, RAD23A, NEDD4L, RNF123, CDKN1B, PSMD6, PSMD7, PSMD4, RNF11, CPSF6, LAPTM5, IQGAP2, MED7, MYH2, EIF4EBP1, Protein Size: 405