Der Kaninchen Polyklonal anti-UBAC1 Antikörper wird verwendet zum Nachweis von UBAC1 in Proben von Human, Maus und Ratte. Er wurde validiert für WB, ELISA, IHC und IF.
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:10000,IF 1:50-200
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1 mg/mL
Buffer
Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Haltbarkeit
12 months
Target
UBAC1
(UBA Domain Containing 1 (UBAC1))
Andere Bezeichnung
GBDR1
Hintergrund
UBAC1, GBDR1, KPC2, UBADC1, Ubiquitin-associated domain-containing protein 1, UBA domain-containing protein 1, E3 ubiquitin-protein ligase subunit KPC2, Glialblastoma cell differentiation-related protein 1, Kip1 ubiquitination-promoting comUbiquitin-associated domain-containing protein 1 is a non-catalytic subunit of the KPC complex that acts as E3 ubiquitin-protein ligase. Required for poly-ubiquitination and proteasome-mediated degradation of CDKN1B during G1 phase of the cell cycle. Diseases associated with UBAC1 include acute cystitis and bladder disease. Among its related pathways are Immune System and Antigen processing- Ubiquitination and Proteasome degradation.