Beclin 1 Antikörper (N-Term)
Kurzübersicht für Beclin 1 Antikörper (N-Term) (ABIN2787756)
Target
Alle Beclin 1 (BECN1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Sequenz
- MVRMVPVLLS LLLLLGPAVP QENQDGRYSL TYIYTGLSKH VEDVPAFQAL
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Homologie
- Cow: 93%, Dog: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 86%, Rabbit: 79%, Rat: 93%
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Produktmerkmale
- This is a rabbit polyclonal antibody against BECN1. It was validated on Western Blot.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human BECN1
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 450 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Beclin 1 (BECN1) (Beclin 1, Autophagy Related (BECN1))
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Andere Bezeichnung
- BECN1
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Hintergrund
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BECN1 plays a central role in autophagy. BECN1 may play a role in antiviral host defense. BECN1 protects against infection by a neurovirulent strain of Sindbis virus.
Alias Symbols: ATG6, VPS30, beclin1
Protein Interaction Partner: AMBRA1, PIK3R4, ATG14, CHAF1A, DYNLL1, UVRAG, PIK3CG, PIK3C3, PARK2, DYNC1I1, DAPK1, CDKN2A, BCL2L1, BCL2, BECN1, DACT1, KIAA0226, UBC, RNF2, BRCA1, WASH1, EXOC8, EXOC4, EXOC2, ULK1, ATG3, USP33, S100A8, MCL1, HSPA1A, Vmp1, PYCARD, TAB2, TAB3, GFI1B, ITCH
Protein Size: 450 -
Molekulargewicht
- 50 kDa
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Gen-ID
- 8678
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NCBI Accession
- NM_003766, NP_003757
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UniProt
- Q14457
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Pathways
- Autophagie
Target
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