SOD2 Antikörper (N-Term)

Produktnummer ABIN2787727

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch SOD2 in WB. Er zeigt eine Reaktivität gegenüber Human, Ratte, Maus, Schaf, Hund, Kaninchen, Rind (Kuh), Meerschweinchen, Ziege, Pferd und Zebrafisch (Danio rerio).

Kurzübersicht für SOD2 Antikörper (N-Term) (ABIN2787727)

Target: SOD2 (Superoxide Dismutase 2, Mitochondrial (SOD2))

Reaktivität: Human, Ratte, Maus, Schaf, Hund, Kaninchen, Rind (Kuh), Meerschweinchen, Ziege, Pferd, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SOD2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SOD2 Antikörper

Bindungsspezifität: N-Term

Sequenz: MLSRAVCGTS RQLAPVLGYL GSRQKHSLPD LPYDYGALEP HINAQIMQLH

Homologie: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against SOD2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SOD2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 222 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu SOD2

Target: SOD2 (Superoxide Dismutase 2, Mitochondrial (SOD2))

Andere Bezeichnung: SOD2

Hintergrund: SOD2 is a member of the iron/manganese superoxide dismutase family. SOD2 is a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene encoding SOD2 have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer.This gene is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Alias Symbols: IPO-B, MNSOD, Mn-SOD, IPOB, MVCD6
Protein Interaction Partner: CYP4F12, UBC, SOD2, SOD1, APP, NABP2, TBL2, ZC3H11A, VAPA, STX7, UBL4A, ALDH5A1, USP36, H2AFX, SUMO1, NOL12, HDHD2, GET4, RPS3A, RAB4A, AURKA,
Protein Size: 222

Molekulargewicht: 24 kDa

Gen-ID: 6648

NCBI Accession: NM_000636, NP_000627

UniProt: P04179

Pathways: Sensory Perception of Sound, Transition Metal Ion Homeostasis, Negative Regulation of intrinsic apoptotic Signaling