SOD2 Antikörper (AA 25-222)

Produktnummer ABIN3021904

Produktdetails anti-SOD2 Antikörper

Target: SOD2 (Superoxide Dismutase 2, Mitochondrial (SOD2))

Bindungsspezifität: AA 25-222

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SOD2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequenz: KHSLPDLPYD YGALEPHINA QIMQLHHSKH HAAYVNNLNV TEEKYQEALA KGDVTAQIAL QPALKFNGGG HINHSIFWTN LSPNGGGEPK GELLEAIKRD FGSFDKFKEK LTAASVGVQG SGWGWLGFNK ERGHLQIAAC PNQDPLQGTT GLIPLLGIDV WEHAYYLQYK NVRPDYLKAI WNVINWENVT ERYMACKK

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 25-222 of human SOD2 (NP_000627.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Referenzen für anti-SOD2 Antikörper (ABIN3021904)

Zhang, Geng, Liu, Li, Gao, Liu, Fang, Chang: "Celastrol ameliorates liver metabolic damage caused by a high-fat diet through Sirt1." in: Molecular metabolism, Vol. 6, Issue 1, pp. 138-147, (2018) (PubMed).

Hu, Nie, Chen, Xie, Fan, Wang, Long, Yan, Zhong, Yan: "Leucine reduces reactive oxygen species levels via an energy metabolism switch by activation of the mTOR-HIF-1α pathway in porcine intestinal epithelial cells." in: The international journal of biochemistry & cell biology, Vol. 89, pp. 42-56, (2017) (PubMed).

Zhong, Wang, Liu, Li, Huang, Zhou, Lin, Lin, Yang: "Ganoderma lucidum polysaccharide peptide prevents renal ischemia reperfusion injury via counteracting oxidative stress." in: Scientific reports, Vol. 5, pp. 16910, (2016) (PubMed).

Chen, An, Chen, Ye, Shen, Han, Zhang, Gao: "Chronic Exercise Training Improved Aortic Endothelial and Mitochondrial Function via an AMPKα2-Dependent Manner." in: Frontiers in physiology, Vol. 7, pp. 631, (2016) (PubMed).

Geng, Zhang, Gao, Tao, Zhang, Liu, Fang, Chang: "Mst1 regulates hepatic lipid metabolism by inhibiting Sirt1 ubiquitination in mice." in: Biochemical and biophysical research communications, Vol. 471, Issue 4, pp. 444-9, (2016) (PubMed).

Zhang, Ouyang, Wang, Shi, Ouyang, Chen, Xiao, Fang: "Mycobacterium tuberculosis Rv2185c contributes to nuclear factor-κB activation." in: Molecular immunology, Vol. 66, Issue 2, pp. 147-53, (2015) (PubMed).

Zhu, Dong, Sun, Ma, Yang, Zhu, Xu: "Rejuvenation of MPTP-induced human neural precursor cell senescence by activating autophagy." in: Biochemical and biophysical research communications, Vol. 464, Issue 2, pp. 526-33, (2015) (PubMed).

Liu, Cui, Li, Xu, Zuo, Fang, Chang: "Cobalt protoporphyrin induces HO-1 expression mediated partially by FOXO1 and reduces mitochondria-derived reactive oxygen species production." in: PLoS ONE, Vol. 8, Issue 11, pp. e80521, (2014) (PubMed).

Details zu SOD2

Target: SOD2 (Superoxide Dismutase 2, Mitochondrial (SOD2))

Andere Bezeichnung: SOD2 (SOD2 Produkte)

Synonyme: LOC100101896 antikoerper, MNSOD antikoerper, GB14346 antikoerper, sod2 antikoerper, MGC88869 antikoerper, Sod2 antikoerper, CG8905 antikoerper, Dmel\\CG8905 antikoerper, Mito SOD antikoerper, Mn SOD antikoerper, Mn-SOD antikoerper, Mn-SOD2 antikoerper, MnSOD antikoerper, MnSODII antikoerper, Mn[2+]SOD antikoerper, SOD antikoerper, SOD-2 antikoerper, SOD2 antikoerper, Sod-2 antikoerper, dSOD2 antikoerper, mitSOD2 antikoerper, mnSOD antikoerper, IPOB antikoerper, MVCD6 antikoerper, cb463 antikoerper, wu:fj33b01 antikoerper, zgc:73051 antikoerper, MnSOD antikoerper, manganese superoxide dismutase antikoerper, superoxide dismutase 2, mitochondrial antikoerper, superoxide dismutase 2 antikoerper, Mn superoxide dismutase antikoerper, Superoxide dismutase 2 (Mn) antikoerper, superoxide dismutase 2 L homeolog antikoerper, BDBG_07234 antikoerper, LOC100101896 antikoerper, MNSOD antikoerper, Sod2 antikoerper, sod2 antikoerper, LbMnSOD4 antikoerper, SOD2 antikoerper, LOC100282741 antikoerper, SOD-2 antikoerper, sod2.L antikoerper

Hintergrund: This gene is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 1.,IPO-B,IPOB,MNSOD,MVCD6,Mn-SOD,SOD2,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Neuroscience,Neurodegenerative Diseases,Cardiovascular,Hypoxia,SOD2

Molekulargewicht: 18 kDa/19 kDa/20 kDa/24 kDa

Gen-ID: 6648

UniProt: P04179

Pathways: Sensory Perception of Sound, Transition Metal Ion Homeostasis, Negative Regulation of intrinsic apoptotic Signaling