DLD Antikörper (Middle Region)

Produktnummer ABIN2787688

Dieses Anti-DLD-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von DLD in WB und IHC. Geeignet für Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Kaninchen, Meerschweinchen, Saccharomyces cerevisiae und Zebrafisch (Danio rerio). Dieses Primary Antibody wurde in 1 Publikation zitiert.

Kurzübersicht für DLD Antikörper (Middle Region) (ABIN2787688)

Target: DLD (Dihydrolipoamide Dehydrogenase (DLD))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Kaninchen, Meerschweinchen, Saccharomyces cerevisiae, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DLD Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-DLD Antikörper

Bindungsspezifität: Middle Region

Sequenz: AGEMVNEAAL ALEYGASCED IARVCHAHPT LSEAFREANL AASFGKSINF

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 93%, Yeast: 86%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against DLD. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human DLD

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 509 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-DLD Antikörper (ABIN2787688)

Ayanniyi, Raji, Adegoke: "Prevalence of asymptomatic sacroiliac joint dysfunction and its association with leg length discrepancies in male students in selected junior secondary schools in Ibadan." in: African journal of medicine and medical sciences, Vol. 37, Issue 1, pp. 37-42, (2008) (PubMed).

Details zu DLD

Target: DLD (Dihydrolipoamide Dehydrogenase (DLD))

Andere Bezeichnung: DLD

Hintergrund: DLD is the L protein of the mitochondrial glycine cleavage system. The L protein, also named dihydrolipoamide dehydrogenase, is also a component of the pyruvate dehydrogenase complex, the alpha-ketoglutarate dehydrogenase complex, and the branched-chain alpha-keto acide dehydrogenase complex. Mutations in this gene have been identified in patients with E3-deficient maple syrup urine disease and lipoamide dehydrogenase deficiency.This gene encodes the L protein of the mitochondrial glycine cleavage system. The L protein, also named dihydrolipoamide dehydrogenase, is also a component of the pyruvate dehydrogenase complex, the alpha-ketoglutarate dehydrogenase complex, and the branched-chain alpha-keto acide dehydrogenase complex. Mutations in this gene have been identified in patients with E3-deficient maple syrup urine disease and lipoamide dehydrogenase deficiency. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: DLDH, E3, GCSL, LAD, PHE3
Protein Interaction Partner: HUWE1, FUS, UBC, SUMO1, NEDD8, MDM2, ASB15, PEPD, LDHA, CKB, ASS1, CNDP2, TNFAIP8, DPP3, RPL23, FN1, ATF2, MRPL11, UBAP2, MRPL37, MRPL13, MRPL42, GGH, UQCRC2, UQCRC1, MRPL23, NONO, NDUFB5, NDUFA9, ETFB, DLAT, DBT, AK2, SIRT7, SLC2A4, PSMD4, OGDH, DLD, PDH
Protein Size: 509

Molekulargewicht: 56 kDa

Gen-ID: 1738

NCBI Accession: NM_000108, NP_000099

UniProt: B2R5X0

Pathways: Ribonucleoside Biosynthetic Process, Cell RedoxHomeostasis