Dynamitin Antikörper (N-Term)
-
- Target Alle Dynamitin (DCTN2) Antikörper anzeigen
- Dynamitin (DCTN2) (Dynactin 2 (p50) (DCTN2))
-
Bindungsspezifität
- N-Term
-
Reaktivität
- Human, Maus, Ratte, Kaninchen, Rind (Kuh), Hund, Pferd, Meerschweinchen, Zebrafisch (Danio rerio)
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser Dynamitin Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB)
- Sequenz
- ADPKYADLPG IARNEPDVYE TSDLPEDDQA EFDAFAQELE ELTSTSVEHI
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against DCTN2. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human DCTN2
- Top Product
- Discover our top product DCTN2 Primärantikörper
-
-
- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
-
Antigen size: 406 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- Target
- Dynamitin (DCTN2) (Dynactin 2 (p50) (DCTN2))
- Andere Bezeichnung
- DCTN2 (DCTN2 Produkte)
- Synonyme
- DCTN2 antikoerper, dctn2 antikoerper, dctn50 antikoerper, dynamitin antikoerper, rbp50 antikoerper, CG8269 antikoerper, DMN antikoerper, Dmel\\CG8269 antikoerper, P50 antikoerper, dDyn antikoerper, dmn antikoerper, dyna antikoerper, l(2)k16109 antikoerper, l(2)k16218 antikoerper, p50 antikoerper, p50/Dmn antikoerper, p50/dynamitin antikoerper, 2310042E05Rik antikoerper, C130077D06Rik antikoerper, C87049 antikoerper, DCTN-50 antikoerper, GMP23-48K antikoerper, RBP50 antikoerper, DCTN50 antikoerper, DYNAMITIN antikoerper, zgc:63867 antikoerper, dynactin subunit 2 antikoerper, dynactin subunit 2 S homeolog antikoerper, Dynactin 2, p50 subunit antikoerper, dynactin 2 antikoerper, dynactin 2 (p50) antikoerper, dynactin subunit 2 L homeolog antikoerper, DCTN2 antikoerper, dctn2.S antikoerper, DCTN2-p50 antikoerper, dctn2 antikoerper, Dctn2 antikoerper, dctn2.L antikoerper
- Hintergrund
-
DCTN2 is a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place.This gene encodes a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: DCTN50, DYNAMITIN, RBP50
Protein Interaction Partner: KIFC3, CCDC172, HAUS1, BLOC1S6, DCTN2, BICD2, DYNC1I1, DCTN1, UBC, FLNB, NUP43, LEO1, SEH1L, ACTR10, DCTN4, DCTN3, ACTR1A, ACTR1B, RABEP1, LMNB1, GADD45A, KPNA2, SMURF1, DYNLRB1, STRN4, RANBP9, TPM4, SNRPA1, PSMD4, PSMD1, PSMC4, PSMC2, POLR2D, POLR2A, MCM
Protein Size: 406 - Molekulargewicht
- 45 kDa
- Gen-ID
- 10540
- NCBI Accession
- NM_006400, NP_006391
- UniProt
- Q13561
- Pathways
- M Phase, Ribonucleoprotein Complex Subunit Organization
-