CPE Antikörper (N-Term)

Produktnummer ABIN2787685

Der Kaninchen-Polyklonal Anti-CPE-Antikörper wurde für WB und IHC validiert. Er ist geeignet zum Nachweis von CPE in Proben aus Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Kaninchen und Zebrafisch (Danio rerio). }

Kurzübersicht für CPE Antikörper (N-Term) (ABIN2787685)

Target: CPE (Carboxypeptidase E (CPE))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CPE Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-CPE Antikörper

Bindungsspezifität: N-Term

Sequenz: GMRRRRRLQQ EDGISFEYHR YPELREALVS VWLQCTAISR IYTVGRSFEG

Homologie: Cow: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against CPE. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CPE

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 476 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CPE

Target: CPE (Carboxypeptidase E (CPE))

Andere Bezeichnung: CPE

Hintergrund: CPE is a carboxypeptidase that cleaves C-terminal amino acid residues and is involved in the biosynthesis of peptide hormones and neurotransmitters, including insulin. It is a peripheral membrane protein. The protein specifically binds regulated secretory pathway proteins, including prohormones, but not constitutively secreted proteinsThis gene encodes a carboxypeptidase that cleaves C-terminal amino acid residues and is involved in the biosynthesis of peptide hormones and neurotransmitters, including insulin. It is a peripheral membrane protein. The protein specifically binds regulated secretory pathway proteins, including prohormones, but not constitutively secreted proteins. Mutations in this gene are implicated in type II diabetes. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: -
Protein Interaction Partner: PRKAA1, UBC, LRIF1, POLDIP2, MED31, ROBO2, POLA2, CHD3, TRH, NTS, GTF3C1, UTP14A, RPA1, PMCH, INS, GCG, GAST, CCK, BDNF,
Protein Size: 476

Molekulargewicht: 52 kDa

Gen-ID: 1363

NCBI Accession: NM_001873, NP_001864

UniProt: P16870

Pathways: Peptide Hormone Metabolism, Synaptic Membrane