CPE Antikörper (N-Term)

Produktnummer ABIN2787685

Der Kaninchen Polyklonal Anti-CPE-Antikörper wurde für WB und IHC validiert. Er ist geeignet, CPE in Proben von Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Kaninchen und Zebrafisch (Danio rerio) zu detektieren.

Kurzübersicht für CPE Antikörper (N-Term) (ABIN2787685)

Target: CPE (Carboxypeptidase E (CPE))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CPE Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-CPE Antikörper

Bindungsspezifität: N-Term

Sequenz: GMRRRRRLQQ EDGISFEYHR YPELREALVS VWLQCTAISR IYTVGRSFEG

Homologie: Cow: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against CPE. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CPE

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 476 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CPE

Target: CPE (Carboxypeptidase E (CPE))

Andere Bezeichnung: CPE

Hintergrund: CPE is a carboxypeptidase that cleaves C-terminal amino acid residues and is involved in the biosynthesis of peptide hormones and neurotransmitters, including insulin. It is a peripheral membrane protein. The protein specifically binds regulated secretory pathway proteins, including prohormones, but not constitutively secreted proteinsThis gene encodes a carboxypeptidase that cleaves C-terminal amino acid residues and is involved in the biosynthesis of peptide hormones and neurotransmitters, including insulin. It is a peripheral membrane protein. The protein specifically binds regulated secretory pathway proteins, including prohormones, but not constitutively secreted proteins. Mutations in this gene are implicated in type II diabetes. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: -
Protein Interaction Partner: PRKAA1, UBC, LRIF1, POLDIP2, MED31, ROBO2, POLA2, CHD3, TRH, NTS, GTF3C1, UTP14A, RPA1, PMCH, INS, GCG, GAST, CCK, BDNF,
Protein Size: 476

Molekulargewicht: 52 kDa

Gen-ID: 1363

NCBI Accession: NM_001873, NP_001864

UniProt: P16870

Pathways: Peptide Hormone Metabolism, Synaptic Membrane