KDM4B Antikörper (Middle Region)
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- Target Alle KDM4B Antikörper anzeigen
- KDM4B (Lysine (K)-Specific Demethylase 4B (KDM4B))
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Bindungsspezifität
- Middle Region
- Reaktivität
- Human, Maus, Ratte, Hund, Pferd, Schwein, Rind (Kuh), Meerschweinchen
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser KDM4B Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- SASRASLKAK LLRRSHRKRS QPKKPKPEDP KFPGEGTAGA ALLEEAGGSV
- Homologie
- Cow: 92%, Dog: 93%, Guinea Pig: 83%, Horse: 93%, Human: 100%, Mouse: 82%, Pig: 93%, Rat: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against JMJD2B. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human JMJD2B
- Top Product
- Discover our top product KDM4B Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 1096 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- KDM4B (Lysine (K)-Specific Demethylase 4B (KDM4B))
- Andere Bezeichnung
- JMJD2B (KDM4B Produkte)
- Synonyme
- KDM4B antikoerper, JMJD2B antikoerper, jmjd2b antikoerper, si:ch211-124a3.4 antikoerper, TDRD14B antikoerper, 4732474L06Rik antikoerper, Jmjd2b antikoerper, mKIAA0876 antikoerper, lysine demethylase 4B antikoerper, lysine (K)-specific demethylase 4B antikoerper, KDM4B antikoerper, kdm4b antikoerper, Kdm4b antikoerper
- Hintergrund
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JMJD2 family proteins are classified into one group with JD2H and TUDOR domains and another group without JD2H or TUDOR domains. Because JMJD2C gene (also known as GASC1 gene) is amplified in esophageal squamous cell carcinoma (ESCC), JMJD2 family genes are cancer-associated genes. Human genes corresponding to KIAA0677, KIAA0876, KIAA0780 and FLJ10251 cDNAs were designated JMJD2A, JMJD2B, JMJD2C, and JMJD2D, respectively. In addition, JMJD2D homologous genes within human genome sequences AP002383.3 and AP001264.4 were designated JMJD2E and JMJD2F, respectively. C2HC2HC2- and C5HC2-type Cys (His) clusters were identified as the region conserved among JMJD2A (1064 aa), JMJD2B (1096 aa), and JMJD2C (1056 aa) proteins. JMJD2A, JMJD2B and JMJD2C consist of JmjN, JmjC, JD2H, and two TUDOR domains.
Alias Symbols: FLJ44906, KDM4B, KIAA0876, JMJD2B
Protein Interaction Partner: UBC, H3F3C, HSP90B1, HSP90AA2P, SMU1, KMT2C, WDR5, ASH2L, KMT2D, RBBP5, HSPA4, HNRNPU, ESR1, MED10,
Protein Size: 1096 - Molekulargewicht
- 122 kDa
- Gen-ID
- 23030
- NCBI Accession
- NM_015015, NP_055830
- UniProt
- O94953
- Pathways
- Warburg Effekt
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