A2BP1 Antikörper (Middle Region)

Produktnummer ABIN2787590

Produktdetails anti-A2BP1 Antikörper

Target: A2BP1 (Ataxin 2-Binding Protein 1 (A2BP1))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Rind (Kuh), Hund, Pferd, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser A2BP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: TAAAYSDRNQ FVFVAADEIS CNTSAVTDEF MLPTPTTTHL LQPPPTALVP

Homologie: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against A2BP1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human A2BP1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 395 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu A2BP1

Target: A2BP1 (Ataxin 2-Binding Protein 1 (A2BP1))

Andere Bezeichnung: A2BP1 (A2BP1 Produkte)

Hintergrund: Ataxin-2 binding protein 1(A2BP1) has an RNP motif that is highly conserved among RNA-binding proteins. This protein binds to the C-terminus of ataxin-2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2). Ataxin-2 is the gene product of the SCA2 gene which causes familial neurodegenerative diseases. Ataxin-2 binding protein 1 and ataxin-2 are both localized in the trans-Golgi network. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been found but their full length nature has not been determined.Ataxin-2 binding protein 1 has an RNP motif that is highly conserved among RNA-binding proteins. This protein binds to the C-terminus of ataxin-2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2). Ataxin-2 is the gene product of the SCA2 gene which causes familial neurodegenerative diseases. Ataxin-2 binding protein 1 and ataxin-2 are both localized in the trans-Golgi network. Four alternatively spliced transcript variants have been found for this gene. Additional transcript variants have been found but their full length nature has not been determined.
Alias Symbols: FOX1, HRNBP1, 2BP1, A2BP1, FOX-1
Protein Interaction Partner: C1orf94, RBPMS, PRR20A, HSFY1, RHOXF2, ALG13, RBFOX1, FAM168A, DAZAP2, MAGED1, BHLHE40, SNRPN, DAB1, CRX, UBC, HSFX1, RBM24, LZTS2, DMRTB1, PCBP4, NOC2L, GCA, RBFOX2, KIFAP3, CELF3, PSMF1, QKI, NUMBL, PRRC2A, ATXN2, ATXN1, HNRNPF, DVL2, ATN1, TNIP1,
Protein Size: 395

Molekulargewicht: 42 kDa

Gen-ID: 54715

NCBI Accession: NM_145893, NP_665900

UniProt: Q9NWB1