RORC Antikörper (N-Term)

Produktnummer ABIN2499787

Produktdetails anti-RORC Antikörper

Target: RORC (RAR-Related Orphan Receptor C (RORC))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Rind (Kuh), Pferd, Meerschweinchen, Hund, Kaninchen, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RORC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: MDRAPQRQHR ASRELLAAKK THTSQIEVIP CKICGDKSSG IHYGVITCEG

Homologie: Cow: 100%, Dog: 96%, Guinea Pig: 79%, Horse: 88%, Human: 100%, Mouse: 92%, Pig: 100%, Rabbit: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against RORC. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human RORC

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu RORC

Target: RORC (RAR-Related Orphan Receptor C (RORC))

Andere Bezeichnung: RORC (RORC Produkte)

Hintergrund: RORC encodes a protein which is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known, however, studies of a similar gene in mice have shown that RORC may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2.
Alias Symbols: NR1F3, RORG, RZR-GAMMA, RZRG, TOR
Protein Interaction Partner: EVI2A, NCOA6, EIF3I, CHD4, EIF4EBP1,
Protein Size: 518

Molekulargewicht: 58 kDa

Gen-ID: 6097

NCBI Accession: NM_005060, NP_005051

UniProt: Q6I9R9

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway