RORC Antikörper (N-Term)
Kurzübersicht für RORC Antikörper (N-Term) (ABIN2787588)
Target
Alle RORC Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Verwendungszweck
- RORC Antibody - N-terminal region
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Sequenz
- MDRAPQRQHR ASRELLAAKK THTSQIEVIP CKICGDKSSG IHYGVITCEG
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Homologie
- Cow: 100%, Dog: 96%, Guinea Pig: 79%, Horse: 88%, Human: 100%, Mouse: 92%, Pig: 100%, Rabbit: 92%
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Produktmerkmale
- This is a rabbit polyclonal antibody against RORC. It was validated on Western Blot.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human RORC
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP58193-100UG
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- prevent freeze-thaw cycles
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- RORC (RAR-Related Orphan Receptor C (RORC))
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Andere Bezeichnung
- RORC
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Hintergrund
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Background Information: RORC encodes a protein which is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known, however, studies of a similar gene in mice have shown that RORC may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2.
Gene Name: RAR-related orphan receptor C
Alternative Symbols: TOR, RORG, RZRG, IMD42, NR1F3, RZR-GAMMA
Protein Name: RAR-related orphan receptor C EMBL AAI10572.1
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Molekulargewicht
- 58kDa
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Gen-ID
- 6097
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NCBI Accession
- NP_005051
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UniProt
- Q6I9R9
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Pathways
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway
Target
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