KDM2A Antikörper (Middle Region)

Produktnummer ABIN2787493

Der Kaninchen Polyklonal anti-KDM2A Antikörper (ABIN2787493) detektiert spezifisch KDM2A in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Hund, Pferd, Kaninchen, Rind (Kuh), Schwein und Meerschweinchen.

Kurzübersicht für KDM2A Antikörper (Middle Region) (ABIN2787493)

Target: KDM2A (Lysine (K)-Specific Demethylase 2A (KDM2A))

Reaktivität: Human, Maus, Ratte, Hund, Pferd, Kaninchen, Rind (Kuh), Schwein, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KDM2A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-KDM2A Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: KDM2A Antibody - middle region

Sequenz: LTPPADKPGQ DNRSKLRNMT DFRLAGLDIT DATLRLIIRH MPLLSRLDLS

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against KDM2A. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human KDM2A

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP57979-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu KDM2A

Target: KDM2A (Lysine (K)-Specific Demethylase 2A (KDM2A))

Andere Bezeichnung: KDM2A

Hintergrund:

Background Information: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains at least six highly degenerated leucine-rich repeats. This family member plays a role in epigenetic silencing. It nucleates at CpG islands and specifically demethylates both mono- and di-methylated lysine-36 of histone H3.

Gene Name: lysine (K)-specific demethylase 2A

Alternative Symbols: FBL7, CXXC8, FBL11, FBXL11, JHDM1A, LILINA

Protein Name: Lysine-specific demethylase 2A

Molekulargewicht: 68kDa

Gen-ID: 22992

NCBI Accession: NP_036440

UniProt: Q9Y2K7

Pathways: Warburg Effekt