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KDM2A Antikörper (Middle Region)

KDM2A Reaktivität: Human, Maus, Ratte, Hund, Schwein, Kaninchen, Rind (Kuh), Pferd, Meerschweinchen WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2787493
  • Target Alle KDM2A Antikörper anzeigen
    KDM2A (Lysine (K)-Specific Demethylase 2A (KDM2A))
    Bindungsspezifität
    • 15
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reaktivität
    • 43
    • 14
    • 8
    • 6
    • 5
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Maus, Ratte, Hund, Schwein, Kaninchen, Rind (Kuh), Pferd, Meerschweinchen
    Wirt
    • 40
    • 2
    • 1
    Kaninchen
    Klonalität
    • 42
    • 1
    Polyklonal
    Konjugat
    • 22
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser KDM2A Antikörper ist unkonjugiert
    Applikation
    • 18
    • 16
    • 16
    • 8
    • 7
    • 7
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    LTPPADKPGQ DNRSKLRNMT DFRLAGLDIT DATLRLIIRH MPLLSRLDLS
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 93%
    Produktmerkmale
    This is a rabbit polyclonal antibody against KDM2A. It was validated on Western Blot.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of Human KDM2A
    Top Product
    Discover our top product KDM2A Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeat freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    KDM2A (Lysine (K)-Specific Demethylase 2A (KDM2A))
    Andere Bezeichnung
    KDM2A (KDM2A Produkte)
    Synonyme
    FBXL11 antikoerper, JHDM1A antikoerper, 100043628 antikoerper, 5530401A10Rik antikoerper, AA589516 antikoerper, AW536790 antikoerper, Cxxc8 antikoerper, Fbl11 antikoerper, Fbl7 antikoerper, Fbxl11 antikoerper, Gm4560 antikoerper, Jhdm1 antikoerper, Jhdm1a antikoerper, lalina antikoerper, KDM2A antikoerper, CXXC8 antikoerper, FBL11 antikoerper, FBL7 antikoerper, LILINA antikoerper, fb76b11 antikoerper, wu:fb76b11 antikoerper, wu:fj11c04 antikoerper, zgc:158441 antikoerper, zgc:158606 antikoerper, lysine demethylase 2A antikoerper, lysine (K)-specific demethylase 2A antikoerper, lysine (K)-specific demethylase 2Aa antikoerper, KDM2A antikoerper, Kdm2a antikoerper, kdm2aa antikoerper
    Hintergrund
    This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains at least six highly degenerated leucine-rich repeats. This family member plays a role in epigenetic silencing. It nucleates at CpG islands and specifically demethylates both mono- and di-methylated lysine-36 of histone H3.
    Alias Symbols: CXXC8, FBL11, FBL7, FBXL11, JHDM1A, LILINA
    Protein Interaction Partner: RB1, E2F1, EED, SKP1, MPG, ZNF512B, UBE2G2, SMAD7, SMAD3, HIST3H3, HIST2H3C, KIAA0368, ELAVL1, UBC, BCL6, FOS, RELA,
    Protein Size: 620
    Molekulargewicht
    68 kDa
    Gen-ID
    22992
    NCBI Accession
    NM_012308, NP_036440
    Pathways
    Warburg Effekt
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