KDM2A Antikörper (Middle Region)

Produktnummer ABIN2787493

Dieses Anti-KDM2A-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von KDM2A in WB. Geeignet für Human, Maus, Ratte, Hund, Pferd, Kaninchen, Rind (Kuh), Schwein und Meerschweinchen.

Kurzübersicht für KDM2A Antikörper (Middle Region) (ABIN2787493)

Target: KDM2A (Lysine (K)-Specific Demethylase 2A (KDM2A))

Reaktivität: Human, Maus, Ratte, Hund, Pferd, Kaninchen, Rind (Kuh), Schwein, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KDM2A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-KDM2A Antikörper

Bindungsspezifität: Middle Region

Sequenz: LTPPADKPGQ DNRSKLRNMT DFRLAGLDIT DATLRLIIRH MPLLSRLDLS

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against KDM2A. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human KDM2A

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu KDM2A

Target: KDM2A (Lysine (K)-Specific Demethylase 2A (KDM2A))

Andere Bezeichnung: KDM2A

Hintergrund: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains at least six highly degenerated leucine-rich repeats. This family member plays a role in epigenetic silencing. It nucleates at CpG islands and specifically demethylates both mono- and di-methylated lysine-36 of histone H3.
Alias Symbols: CXXC8, FBL11, FBL7, FBXL11, JHDM1A, LILINA
Protein Interaction Partner: RB1, E2F1, EED, SKP1, MPG, ZNF512B, UBE2G2, SMAD7, SMAD3, HIST3H3, HIST2H3C, KIAA0368, ELAVL1, UBC, BCL6, FOS, RELA,
Protein Size: 620

Molekulargewicht: 68 kDa

Gen-ID: 22992

NCBI Accession: NM_012308, NP_036440

Pathways: Warburg Effekt