PER1 Antikörper (N-Term)

Produktnummer ABIN2787442

Produktdetails anti-PER1 Antikörper

Target: PER1 (Period Homolog 1 (Drosophila) (PER1))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Pferd, Meerschweinchen, Rind (Kuh), Hund, Schwein, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PER1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: SGPLEGADGG GDPRPGESFC PGGVPSPGPP QHRPCPGPSL ADDTDANSNG

Homologie: Cow: 92%, Dog: 93%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against PER1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of human PER1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PER1

Target: PER1 (Period Homolog 1 (Drosophila) (PER1))

Andere Bezeichnung: PER1 (PER1 Produkte)

Hintergrund: This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene may increase the risk of getting certain cancers. Alternative splicing has been observed in this gene, however, these variants have not been fully described.
Alias Symbols: PER, hPER, RIGUI
Protein Size: 294

Molekulargewicht: 32 kDa

Gen-ID: 5187

NCBI Accession: NM_002616, NP_002607

UniProt: O15534

Pathways: Photoperiodism