RCAN1 Antikörper (N-Term)
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- Target Alle RCAN1 Antikörper anzeigen
- RCAN1 (Regulator of Calcineurin 1 (RCAN1))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Maus, Ratte, Hund
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser RCAN1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- MEDGVAGPQL GAAAEAAEAA EARARPGVTL RPFAPLSGAA EADEGGGDWS
- Homologie
- Dog: 93%, Human: 100%, Mouse: 77%, Rat: 92%
- Produktmerkmale
- This is a rabbit polyclonal antibody against RCAN1. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human RCAN1
- Top Product
- Discover our top product RCAN1 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 252 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- RCAN1 (Regulator of Calcineurin 1 (RCAN1))
- Andere Bezeichnung
- RCAN1 (RCAN1 Produkte)
- Synonyme
- ADAPT78 antikoerper, CSP1 antikoerper, DSC1 antikoerper, DSCR1 antikoerper, MCIP1 antikoerper, RCN1 antikoerper, RCAN1 antikoerper, 2410048A02Rik antikoerper, AA408855 antikoerper, AI429645 antikoerper, AL024459 antikoerper, AV028423 antikoerper, Adapt78 antikoerper, CALP1L antikoerper, Dscr1 antikoerper, Mcip1 antikoerper, dscr1 antikoerper, rcan1 antikoerper, wu:fr92c05 antikoerper, adapt78 antikoerper, csp1 antikoerper, dsc1 antikoerper, mcip1 antikoerper, MGC53636 antikoerper, rcn1 antikoerper, MGC69428 antikoerper, regulator of calcineurin 1 antikoerper, regulator of calcineurin 1b antikoerper, regulator of calcineurin 1 L homeolog antikoerper, Down syndrome critical region gene 1 antikoerper, RCAN1 antikoerper, Rcan1 antikoerper, rcan1b antikoerper, rcan1.L antikoerper, dscr1 antikoerper, rcan1 antikoerper
- Hintergrund
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RCAN1 interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease.
Alias Symbols: ADAPT78, CSP1, DSC1, DSCR1, MCIP1, RCN1
Protein Interaction Partner: UBC, PPP3CA, NEDD8, APP, FBXW11, BTRC, FBXW4, TOLLIP, TRAF6, IRAK1, HSP90AA1, STAT2, GSK3B, MAP3K3, MAPK3, UXT,
Protein Size: 252 - Molekulargewicht
- 28 kDa
- Gen-ID
- 1827
- NCBI Accession
- NM_004414, NP_004405
- UniProt
- P53805
- Pathways
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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