OPA1 Antikörper (N-Term)

Produktnummer ABIN2787355

Der Kaninchen Polyklonal anti-OPA1 Antikörper (ABIN2787355) detektiert spezifisch OPA1 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte, Maus, Zebrafisch (Danio rerio), Hund, Rind (Kuh), Meerschweinchen, Pferd und Kaninchen.

Kurzübersicht für OPA1 Antikörper (N-Term) (ABIN2787355)

Target: OPA1 (Optic Atrophy 1 (Autosomal Dominant) (OPA1))

Reaktivität: Human, Ratte, Maus, Zebrafisch (Danio rerio), Hund, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser OPA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-OPA1 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: OPA1 Antibody - N-terminal region

Sequenz: SPEETAFRAT DRGSESDKHF RKVSDKEKID QLQEELLHTQ LKYQRILERL

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against OPA1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP57715-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu OPA1

Target: OPA1 (Optic Atrophy 1 (Autosomal Dominant) (OPA1))

Andere Bezeichnung: OPA1

Hintergrund:

Background Information: This gene product is a nuclear-encoded mitochondrial protein with similarity to dynamin-related GTPases. It is a component of the mitochondrial network. Mutations in this gene have been associated with optic atrophy type 1, which is a dominantly inherited optic neuropathy resulting in progressive loss of visual acuity, leading in many cases to legal blindness. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Name: Optic atrophy 1 (autosomal dominant)

Alternative Symbols: NPG, NTG, MGM1, BERHS, largeG, MTDPS14

Protein Name: Mitochondrial dynamin-like 120 kDa protein EMBL ADP90061.1

Molekulargewicht: 102kDa

Gen-ID: 4976

NCBI Accession: NP_570844

UniProt: E5KLK2

Pathways: Tube Formation