OPA1 Antikörper (N-Term)

Produktnummer ABIN2787355

Produktdetails anti-OPA1 Antikörper

Target: OPA1 (Optic Atrophy 1 (Autosomal Dominant) (OPA1))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Kaninchen, Zebrafisch (Danio rerio), Hund, Rind (Kuh), Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser OPA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: SPEETAFRAT DRGSESDKHF RKVSDKEKID QLQEELLHTQ LKYQRILERL

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against OPA1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 924 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu OPA1

Target: OPA1 (Optic Atrophy 1 (Autosomal Dominant) (OPA1))

Andere Bezeichnung: OPA1 (OPA1 Produkte)

Synonyme: 1200011N24Rik antikoerper, AI225888 antikoerper, AI847218 antikoerper, lilr3 antikoerper, mKIAA0567 antikoerper, MGM1 antikoerper, NPG antikoerper, NTG antikoerper, largeG antikoerper, fk62d06 antikoerper, wu:fb77a10 antikoerper, wu:fk62d06 antikoerper, zgc:92092 antikoerper, OPA1, mitochondrial dynamin like GTPase antikoerper, optic atrophy 1 (autosomal dominant) antikoerper, Opa1 antikoerper, OPA1 antikoerper, opa1 antikoerper

Hintergrund: This gene product is a nuclear-encoded mitochondrial protein with similarity to dynamin-related GTPases. It is a component of the mitochondrial network. Mutations in this gene have been associated with optic atrophy type 1, which is a dominantly inherited optic neuropathy resulting in progressive loss of visual acuity, leading in many cases to legal blindness. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: FLJ12460, KIAA0567, MGM1, NPG, NTG, largeG
Protein Interaction Partner: UBC, PARK2, MYC, HSP90AA5P, NIT2, HTRA2, NPTX1, NDUFS8, NDUFS1, NDUFA9, ILF3, HADHB, ECH1, DNASE2, APP, SMAD3, SMAD2, CAND1, CUL3, ELAVL1, MME,
Protein Size: 924

Molekulargewicht: 102 kDa

Gen-ID: 4976

NCBI Accession: NM_130831, NP_570844

UniProt: E5KLK2

Pathways: Tube Formation