Mitofusin 1 (MFN1) (Middle Region) Antikörper

Details zu Produkt Nr. ABIN2787347, Anbieter: Anmelden zum Anzeigen
Antigen
  • mfn1
  • zgc:66150
  • mitofusin-1
  • MFN1
  • MFN2
  • hfzo1
  • hfzo2
  • 2310002F04Rik
  • 6330416C07Rik
  • D3Ertd265e
  • HR2
  • mKIAA4032
  • Fzo1b
  • mitofusin 1b
  • mitofusin 1
  • mitofusin 1 S homeolog
  • mfn1b
  • MFN1
  • mfn1.S
  • mfn1
  • Mfn1
Epitop
Middle Region
21
16
13
10
9
9
8
8
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Reaktivität
Rind (Kuh), Hund, Pferd, Human, Maus, Schwein, Kaninchen, Ratte (Rattus)
111
73
68
6
6
5
5
4
2
2
1
1
1
1
1
1
Wirt
Kaninchen
83
34
13
2
Klonalität
Polyklonal
Konjugat
Unkonjugiert
6
5
5
4
3
3
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Western Blotting (WB)
101
61
42
38
34
28
15
13
4
2
2
1
1
Optionen
Hersteller
Anmelden zum Anzeigen
Hersteller Produkt- Nr.
Anmelden zum Anzeigen
Immunogen The immunogen is a synthetic peptide directed towards the middle region of human MFN1
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN980021.
Sequenz QVDITQKQLE EEIARLPKEI DQLEKIQNNS KLLRNKAVQL ENELENFTKQ
Homologie Cow: 100%, Dog: 100%, Horse: 86%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 100%, Rat: 100%
Produktmerkmale This is a rabbit polyclonal antibody against MFN1. It was validated on Western Blot using a cell lysate as a positive control.
Reinigung Affinity Purified
Antigen
Andere Bezeichnung MFN1 (MFN1 Antibody Abstract)
Hintergrund The protein encoded by this gene is a mediator of mitochondrial fusion. This protein and mitofusin 2 are homologs of the Drosophila protein fuzzy onion (Fzo). They are mitochondrial membrane proteins that interact with each other to facilitate mitochondrial targeting.
Alias Symbols: DKFZp762F247, FLJ20693, MGC41806, hfzo1, hfzo2
Protein Interaction Partner: PARK2, MARCH5, UBC, TER94, MAVS, CCNB1, ILF2, BAK1,
Protein Size: 741
Molekulargewicht 84 kDa
Gen-ID 55669
NCBI Accession NM_033540, NP_284941
UniProt Q8R4Z9
Applikations-hinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 741 AA

Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Bilder des Herstellers
Western Blotting (WB) image for anti-Mitofusin 1 (MFN1) (Middle Region) antibody (ABIN2787347) WB Suggested Anti-MFN1 Antibody Titration: 0.2-1 ug/mlPositive Control: Human Placenta
Western Blotting (WB) image for anti-Mitofusin 1 (MFN1) (Middle Region) antibody (ABIN2787347) WB Suggested Anti-MFN1 Antibody Titration: 0.2-1 µg/mL Positive Control: Human Plac...
Produkt verwendet in: Bonala, McFarlane, Ang, Lim, Lee, Chua, Lokireddy, Sreekanth, Leow, Meng, Shyong, Lee, Gluckman, Sharma, Kambadur: "Pid1 induces insulin resistance in both human and mouse skeletal muscle during obesity." in: Molecular endocrinology (Baltimore, Md.), Vol. 27, Issue 9, pp. 1518-35, 2013 (PubMed).

Papanicolaou, Khairallah, Ngoh, Chikando, Luptak, OShea, Riley, Lugus, Colucci, Lederer, Stanley, Walsh: "Mitofusin-2 maintains mitochondrial structure and contributes to stress-induced permeability transition in cardiac myocytes." in: Molecular and cellular biology, Vol. 31, Issue 6, pp. 1309-28, 2011 (PubMed).

Haben Sie etwas anderes gesucht?