MFN1 Antikörper (Middle Region)

Produktnummer ABIN2787347

Zitiert in 2+ Publikationen. Der Kaninchen Polyklonal anti-MFN1 Antikörper (ABIN2787347) detektiert spezifisch MFN1 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Hund, Kaninchen, Pferd, Rind (Kuh) und Schwein.

Kurzübersicht für MFN1 Antikörper (Middle Region) (ABIN2787347)

Target: MFN1 (Mitofusin 1 (MFN1))

Reaktivität: Human, Maus, Ratte, Hund, Kaninchen, Pferd, Rind (Kuh), Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MFN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-MFN1 Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: MFN1 Antibody - middle region

Sequenz: QVDITQKQLE EEIARLPKEI DQLEKIQNNS KLLRNKAVQL ENELENFTKQ

Homologie: Cow: 100%, Dog: 100%, Horse: 86%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against MFN1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human MFN1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP57702-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-MFN1 Antikörper (ABIN2787347)

Bonala, McFarlane, Ang, Lim, Lee, Chua, Lokireddy, Sreekanth, Leow, Meng, Shyong, Lee, Gluckman, Sharma, Kambadur: "Pid1 induces insulin resistance in both human and mouse skeletal muscle during obesity." in: Molecular endocrinology (Baltimore, Md.), Vol. 27, Issue 9, pp. 1518-35, (2013) (PubMed).

Papanicolaou, Khairallah, Ngoh, Chikando, Luptak, OShea, Riley, Lugus, Colucci, Lederer, Stanley, Walsh: "Mitofusin-2 maintains mitochondrial structure and contributes to stress-induced permeability transition in cardiac myocytes." in: Molecular and cellular biology, Vol. 31, Issue 6, pp. 1309-28, (2011) (PubMed).

Details zu MFN1

Target: MFN1 (Mitofusin 1 (MFN1))

Andere Bezeichnung: MFN1

Hintergrund:

Background Information: The protein encoded by this gene is a mediator of mitochondrial fusion. This protein and mitofusin 2 are homologs of the Drosophila protein fuzzy onion (Fzo). They are mitochondrial membrane proteins that interact with each other to facilitate mitochondrial targeting.

Gene Name: Mitofusin 1

Alternative Symbols: hfzo1, hfzo2

Protein Name: Mitofusin-1

Molekulargewicht: 84 kDa

Gen-ID: 55669

NCBI Accession: NP_284941

UniProt: Q8R4Z9