MFN1 Antikörper (Middle Region)

Produktnummer ABIN2787347

Dieses Anti-MFN1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von MFN1 in WB. Geeignet für Human, Maus, Ratte, Kaninchen, Hund, Pferd, Rind (Kuh) und Schwein. Dieses Primary Antibody wurde in 2+ Publikationen zitiert.

Kurzübersicht für MFN1 Antikörper (Middle Region) (ABIN2787347)

Target: MFN1 (Mitofusin 1 (MFN1))

Reaktivität: Human, Maus, Ratte, Kaninchen, Hund, Pferd, Rind (Kuh), Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MFN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-MFN1 Antikörper

Bindungsspezifität: Middle Region

Sequenz: QVDITQKQLE EEIARLPKEI DQLEKIQNNS KLLRNKAVQL ENELENFTKQ

Homologie: Cow: 100%, Dog: 100%, Horse: 86%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against MFN1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human MFN1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 741 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-MFN1 Antikörper (ABIN2787347)

Bonala, McFarlane, Ang, Lim, Lee, Chua, Lokireddy, Sreekanth, Leow, Meng, Shyong, Lee, Gluckman, Sharma, Kambadur: "Pid1 induces insulin resistance in both human and mouse skeletal muscle during obesity." in: Molecular endocrinology (Baltimore, Md.), Vol. 27, Issue 9, pp. 1518-35, (2013) (PubMed).

Papanicolaou, Khairallah, Ngoh, Chikando, Luptak, OShea, Riley, Lugus, Colucci, Lederer, Stanley, Walsh: "Mitofusin-2 maintains mitochondrial structure and contributes to stress-induced permeability transition in cardiac myocytes." in: Molecular and cellular biology, Vol. 31, Issue 6, pp. 1309-28, (2011) (PubMed).

Details zu MFN1

Target: MFN1 (Mitofusin 1 (MFN1))

Andere Bezeichnung: MFN1

Hintergrund: The protein encoded by this gene is a mediator of mitochondrial fusion. This protein and mitofusin 2 are homologs of the Drosophila protein fuzzy onion (Fzo). They are mitochondrial membrane proteins that interact with each other to facilitate mitochondrial targeting.
Alias Symbols: DKFZp762F247, FLJ20693, MGC41806, hfzo1, hfzo2
Protein Interaction Partner: PARK2, MARCH5, UBC, TER94, MAVS, CCNB1, ILF2, BAK1,
Protein Size: 741

Molekulargewicht: 84 kDa

Gen-ID: 55669

NCBI Accession: NM_033540, NP_284941

UniProt: Q8R4Z9