BBS4 Antikörper (N-Term)

Produktnummer ABIN2787344

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch BBS4 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Hund, Pferd, Rind (Kuh), Kaninchen, Zebrafisch (Danio rerio), Meerschweinchen und Schwein.

Kurzübersicht für BBS4 Antikörper (N-Term) (ABIN2787344)

Target: BBS4 (Bardet-Biedl Syndrome 4 (BBS4))

Reaktivität: Human, Maus, Ratte, Hund, Pferd, Rind (Kuh), Kaninchen, Zebrafisch (Danio rerio), Meerschweinchen, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BBS4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-BBS4 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: BBS4 Antibody - N-terminal region

Sequenz: YVQALIFRLE GNIQESLELF QTCAVLSPQS ADNLKQVARS LFLLGKHKAA

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against BBS4. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human BBS4

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP57695-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu BBS4

Target: BBS4 (Bardet-Biedl Syndrome 4 (BBS4))

Andere Bezeichnung: BBS4

Hintergrund:

Background Information: This gene is a member of the Bardet-Biedl syndrome (BBS) gene family. Bardet-Biedl syndrome is an autosomal recessive disorder characterized by severe pigmentary retinopathy, obesity, polydactyly, renal malformation and mental retardation. The proteins encoded by BBS gene family members are structurally diverse. The similar phenotypes exhibited by mutations in BBS gene family members are likely due to the protein's shared roles in cilia formation and function. Many BBS proteins localize to the basal bodies, ciliary axonemes, and pericentriolar regions of cells. BBS proteins may also be involved in intracellular trafficking via microtubule-related transport. The protein encoded by this gene has sequence similarity to O-linked N-acetylglucosamine (O-GlcNAc) transferases in plants and archaebacteria and in human forms a multi-protein "BBSome" complex with six other BBS proteins. Alternative splice variants have been described but their predicted protein products have not been experimentally verified.

Gene Name: Bardet-Biedl syndrome 4

Alternative Symbols: -

Protein Name: Bardet-Biedl syndrome 4 protein

Molekulargewicht: 58kDa

Gen-ID: 585

NCBI Accession: NP_149017

UniProt: Q96RK4

Pathways: Hedgehog Signalweg, Tube Formation, Maintenance of Protein Location