BBS4 Antikörper (N-Term)

Produktnummer ABIN2787344

Produktdetails anti-BBS4 Antikörper

Target: BBS4 (Bardet-Biedl Syndrome 4 (BBS4))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Hund, Schwein, Pferd, Rind (Kuh), Kaninchen, Zebrafisch (Danio rerio), Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BBS4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: YVQALIFRLE GNIQESLELF QTCAVLSPQS ADNLKQVARS LFLLGKHKAA

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against BBS4. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human BBS4

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 519 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu BBS4

Target: BBS4 (Bardet-Biedl Syndrome 4 (BBS4))

Andere Bezeichnung: BBS4 (BBS4 Produkte)

Synonyme: CG13232 antikoerper, Dmel\\CG13232 antikoerper, zgc:152964 antikoerper, AW537059 antikoerper, AW742241 antikoerper, D9Ertd464e antikoerper, Bardet-Biedl syndrome 4 antikoerper, bardet-biedl syndrome 4 antikoerper, Bardet-Biedl syndrome 4 (human) antikoerper, BBS4 antikoerper, bbs4 antikoerper, Bbs4 antikoerper

Hintergrund: This gene is a member of the Bardet-Biedl syndrome (BBS) gene family. Bardet-Biedl syndrome is an autosomal recessive disorder characterized by severe pigmentary retinopathy, obesity, polydactyly, renal malformation and mental retardation. The proteins encoded by BBS gene family members are structurally diverse. The similar phenotypes exhibited by mutations in BBS gene family members are likely due to the protein's shared roles in cilia formation and function. Many BBS proteins localize to the basal bodies, ciliary axonemes, and pericentriolar regions of cells. BBS proteins may also be involved in intracellular trafficking via microtubule-related transport. The protein encoded by this gene has sequence similarity to O-linked N-acetylglucosamine (O-GlcNAc) transferases in plants and archaebacteria and in human forms a multi-protein "BBSome" complex with six other BBS proteins. Alternative splice variants have been described but their predicted protein products have not been experimentally verified.
Alias Symbols: -
Protein Interaction Partner: MYOG, HSCB, FHOD1, EXOC7, EIF3A, PCM1, PAX2, KRT18, EPAS1, EEF1A1, DCTN1, CALCA, BHMT, ALDOB, ACTB, CUL3, UBC,
Protein Size: 519

Molekulargewicht: 58 kDa

Gen-ID: 585

NCBI Accession: NM_033028, NP_149017

UniProt: Q96RK4

Pathways: Hedgehog Signalweg, Tube Formation, Maintenance of Protein Location