GREM2 Antikörper (N-Term)

Produktnummer ABIN2787313

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch GREM2 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Meerschweinchen, Hund und Pferd.

Kurzübersicht für GREM2 Antikörper (N-Term) (ABIN2787313)

Target: GREM2 (Gremlin 2 (GREM2))

Reaktivität: Human, Maus, Ratte, Meerschweinchen, Hund, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GREM2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-GREM2 Antikörper

Bindungsspezifität: N-Term

Sequenz: MFWKLSLSLF LVAVLVKVAE ARKNRPAGAI PSPYKDGSSN NSERWQHQIK

Homologie: Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against GREM2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GREM2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 168 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu GREM2

Target: GREM2 (Gremlin 2 (GREM2))

Andere Bezeichnung: GREM2

Hintergrund: This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation.
Alias Symbols: CKTSF1B2, DAND3, PRDC
Protein Interaction Partner: BMP4, BMP2,
Protein Size: 168

Molekulargewicht: 17 kDa

Gen-ID: 64388

NCBI Accession: NM_022469, NP_071914

UniProt: Q9H772