WFDC1 Antikörper (N-Term)

Produktnummer ABIN2787262

Produktdetails anti-WFDC1 Antikörper

Target: WFDC1 (WAP Four-Disulfide Core Domain 1 (WFDC1))

Bindungsspezifität: N-Term

Reaktivität: Human, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser WFDC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: WKRALPARLA EKSRAEEAGA PGGPRQPRAD RCPPPPRTLP PGACQAARCQ

Homologie: Dog: 91%, Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against WFDC1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human WFDC1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 220 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu WFDC1

Target: WFDC1 (WAP Four-Disulfide Core Domain 1 (WFDC1))

Andere Bezeichnung: WFDC1 (WFDC1 Produkte)

Synonyme: WFDC1 antikoerper, zgc:158671 antikoerper, PS20 antikoerper, 2310058A03Rik antikoerper, ps20 antikoerper, WAP four-disulfide core domain 1 antikoerper, WFDC1 antikoerper, wfdc1 antikoerper, Wfdc1 antikoerper

Hintergrund: This gene encodes a member of the WAP-type four disulfide core domain family. The WAP-type four-disulfide core domain, or WAP signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. The encoded protein shares 81 % amino acid identity with the rat ps20 protein, which was originally identified as a secreted growth inhibitor. This gene is mapped to chromosome 16q24, an area of frequent loss of heterozygosity in cancers, including prostate, breast and hepatocellular cancers and Wilms' tumor. Owing to its location and a possible growth inhibitory property of its gene product, this gene is suggested to be a tumor suppressor gene.
Alias Symbols: PS20
Protein Interaction Partner: EZR, ZNF677, RAB40B, FOSL1, XRCC2,
Protein Size: 220

Molekulargewicht: 21 kDa

Gen-ID: 58189

NCBI Accession: NM_021197, NP_067020

UniProt: Q9HC57