Der Kaninchen Polyklonal anti-WFDC1 Antikörper (ABIN7232140) detektiert spezifisch WFDC1 in WB und ELISA.
Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1 mg/mL
Buffer
PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
Konservierungsmittel
ProClin
Vorsichtsmaßnahmen
This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Haltbarkeit
12 months
Target
WFDC1
(WAP Four-Disulfide Core Domain 1 (WFDC1))
Andere Bezeichnung
WFDC1
Hintergrund
WAP four-disulfide core domain protein 1, Prostate stromal protein ps20, ps20 growth inhibitorWFDC1 (WAP Four-Disulfide Core Domain 1) is a Protein Coding gene. WFDC1 encodes a member of the WAP-type four disulfide core domain family. The WAP-type four-disulfide core domain contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. WFDC1 is mapped to chromosome 16q24, an area of frequent loss of heterozygosity in cancers, including prostate, breast and hepatocellular cancers and Wilms' tumor. WFDC1 is downregulated in many cancer types and may be involved in the inhibition of cell proliferation. The encoded protein may also play a role in the susceptibility of certain CD4 memory T cells to human immunodeficiency virus infection. Alternative splicing results in multiple transcript variants.